The ability of green silver nanoparticles to prevent negative effects of X-ray on some physiological parameters in albino male rats

Abstract EN

The present study was used 20 adult male rats that distributed to four groups (each group consist 5 rats); control group that administrated normal saline, rats group that exposure to X ray for two weeks, rats group that exposure to X ray with 50ug of green silver nanoparticles for two weeks, rats group that exposure to X ray with 100ug of green silver nanoparticles for two weeks.

The results show high significant increased (P < 0.01) in levels of malonedialdehyied (MDA), and high significant decreased (P < 0.01) in levels glutathione (GSH) and significant increased (P < 0.01) in levels of Alanine Aminotransferase (ALT), Aspartate Aminotransferase (AST), Alkaline Phosphatase (ALP), compared with control group.

Histological section of liver sections that prepared from rats group that exposure to X ray show lymphocytes infiltration, thickening wall and congestion of central veins.

when used green silver nanoparticles with X ray, the results showed non-significant changes (P < 0.01) in all parameters compared with control group.

It was concluded that green silver nanoparticles has been potential role against the negative effects of X ray in adult male rats.