Effects of "Satureja hortensis L." on improving adult gastroesophageal reflux disease : a double-blind, randomized, controlled, clinical trial
Joint Authors
Mosavat, Sayyid Hamad Allah
Kashani, Amir Husayn Faghihi
Heydarirad, Ghazalah
Yusufi, Sayyid Sedighe
Choopani, Rasul
Varnosfaderani, Shahnaz Karkon
Kamalinejad, Muhammad
Source
Iranian Red Crescent Medical Journal
Issue
Vol. 20, Issue 2 (28 Feb. 2018), pp.1-7, 7 p.
Publisher
Publication Date
2018-02-28
Country of Publication
United Arab Emirates
No. of Pages
7
Main Subjects
Abstract EN
Background: Gastro-esophageal reflux disease (GERD) is one of the most widespread gastrointestinal disorders.
In addition, there is increasing evidence that not all patients respond to its current remedies.
Objectives: The aim of this pilot study was to investigate the effect of “Satureja hortensis L.” on improving the symptoms of mild to moderate GERD in adults.
Methods: In this double-blind, randomized, controlled, clinical trial, we evaluated the efficacy of “Satureja hortensis L.” compared to placebo in the symptoms of GERD in fifty-eight adults with GERD who referred to Hazrat Rasool-e-Akram hospital in Tehran, Iran, in 2015.
In order to assess GERD symptoms, a standardized questionnaire of frequency scale (FSSG) was used before and after the intervention.
Results: Regarding within-group changes, a significant decrease was observed in FSSG, dysmotility-like symptoms and acid reflux related scores in both groups of the study after the intervention compared to baseline (P < 0.001).
Regarding between-group analysis, no significant differences were observed between the two groups in terms of FSSG total scores (0.05 < P).
Conclusions: According to the results of the current study, Satureja hortensis L.
with the dose of 500 mg three times per day failed to improve the symptoms of GERD in adults compared to placebo.
The significant reductions in the GERD scores in both groups seem to be related to the lifestyle modification that was prescribed to both groups.
American Psychological Association (APA)
Kashani, Amir Husayn Faghihi& Heydarirad, Ghazalah& Yusufi, Sayyid Sedighe& Choopani, Rasul& Kamalinejad, Muhammad& Varnosfaderani, Shahnaz Karkon…[et al.]. 2018. Effects of "Satureja hortensis L." on improving adult gastroesophageal reflux disease : a double-blind, randomized, controlled, clinical trial. Iranian Red Crescent Medical Journal،Vol. 20, no. 2, pp.1-7.
https://search.emarefa.net/detail/BIM-840445
Modern Language Association (MLA)
Kashani, Amir Husayn Faghihi…[et al.]. Effects of "Satureja hortensis L." on improving adult gastroesophageal reflux disease : a double-blind, randomized, controlled, clinical trial. Iranian Red Crescent Medical Journal Vol. 20, no. 2 (Feb. 2018), pp.1-7.
https://search.emarefa.net/detail/BIM-840445
American Medical Association (AMA)
Kashani, Amir Husayn Faghihi& Heydarirad, Ghazalah& Yusufi, Sayyid Sedighe& Choopani, Rasul& Kamalinejad, Muhammad& Varnosfaderani, Shahnaz Karkon…[et al.]. Effects of "Satureja hortensis L." on improving adult gastroesophageal reflux disease : a double-blind, randomized, controlled, clinical trial. Iranian Red Crescent Medical Journal. 2018. Vol. 20, no. 2, pp.1-7.
https://search.emarefa.net/detail/BIM-840445
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 6-7
Record ID
BIM-840445