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Evaluation of humeral immunity against three hydatid cyst antigens of camels using secondary cyst development in Rabbit model
Joint Authors
Mahdi, Ulfat A.
Musa, Walid M.
Abd al-Wahhab, Azzah M.
al-Jamil, Suhaylah M.
Source
Journal of the Egyptian Society of Parasitology
Issue
Vol. 47, Issue 3 (31 Dec. 2017), pp.623-631, 9 p.
Publisher
The Egyptian Society of Parasitology
Publication Date
2017-12-31
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Cystic echinococcosis (CE) is one of the commonest zoonotic parasitosis of worldwide distrib-ution.
This study induced a protective immunity against secondary hydatidosis by using conven-tional vaccination approaches and evaluated the accompanied humeral immune response.
For antigen preparation Hydatid cysts (HC) were collected from camels slaughtered at Cairo abattoir, during 2015.Three groups of male rabbits were immunized subcutaneously with crude Hydatid cyst fluid (CHCF), partially purified Hydatid cyst fluid (ppHCF) and protoscolices (PSC) antigens.
After two boosters, rabbits were challenged intra peritoneally with 2000 viable protoscolices, and the humeral immune response was analyzed using ELISA.
Percent of protection against HC was 93.0 %, 88.4 % and 86.0 % in immunized rabbits with ppHCF, PSC and CHCF antigens respectively.
Antibody level in immunized group with ppHCF antigen on day 28 was higher than before immunization and was higher than that in CHCF and PSC antigen groups.
The results of this article indicate that ppHCF antigen can be used as a candidate for vaccine production
American Psychological Association (APA)
Musa, Walid M.& Mahdi, Ulfat A.& Abd al-Wahhab, Azzah M.& al-Jamil, Suhaylah M.. 2017. Evaluation of humeral immunity against three hydatid cyst antigens of camels using secondary cyst development in Rabbit model. Journal of the Egyptian Society of Parasitology،Vol. 47, no. 3, pp.623-631.
https://search.emarefa.net/detail/BIM-840803
Modern Language Association (MLA)
Musa, Walid M.…[et al.]. Evaluation of humeral immunity against three hydatid cyst antigens of camels using secondary cyst development in Rabbit model. Journal of the Egyptian Society of Parasitology Vol. 47, no. 3 (Dec. 2017), pp.623-631.
https://search.emarefa.net/detail/BIM-840803
American Medical Association (AMA)
Musa, Walid M.& Mahdi, Ulfat A.& Abd al-Wahhab, Azzah M.& al-Jamil, Suhaylah M.. Evaluation of humeral immunity against three hydatid cyst antigens of camels using secondary cyst development in Rabbit model. Journal of the Egyptian Society of Parasitology. 2017. Vol. 47, no. 3, pp.623-631.
https://search.emarefa.net/detail/BIM-840803
Data Type
Journal Articles
Language
English
Notes
Includes appendices : p. 629-631
Record ID
BIM-840803