The effect of perioperative use of dexmedetomidine on pediatric patients with pulmonary hypertension undergoing congenital cardiac surgery
Joint Authors
Abd al-Hamid, Hadil M.
Abd al-Aziz, Mayy M.
Umar, Ahmad H. Ali
Source
Ain Shams Journal of Anesthesiology
Issue
Vol. 10, Issue 1 (31 Mar. 2017), pp.10-14, 5 p.
Publisher
Ain Shams University Faculty of Medicine Department of Anesthesiology
Publication Date
2017-03-31
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Background Anesthetic management of a pediatric patient with pulmonary arterial hypertension (PAH) poses an enormous challenge.
The objective of this study was to evaluate the ability of dexmedetomidine to reduce the pulmonary artery pressure in pediatric patients with PAH undergoing cardiac surgery.
Patients and method Seventy patients diagnosed with PAH were enrolled in this study.
The patients were randomized into two groups: group D received dexmedetomidine infusion of 1 μg/ kg/h for one hour, which was reduced to 0.5 μg/kg/h throughout the surgery until extubation in the post anesthesia care unit (PACU), and group C received 0.9% normal saline in the same volume.
Pulmonary artery systolic pressure (PASP) and systemic systolic blood pressure (SSBP) were recorded throughout surgery and postoperatively in the PACU.
The need for vasodilator and sedative drugs and the time of extubation and ICU stay were recorded for all patients.
Results The patients in the dexmedetomidine group showed a significant decrease in PASP and PASP/SSBP ratio during surgery and throughout the first 24 h in the PACU (P<0.001).
The dexmedetomidine group required a significantly lower amount of vasodilator drugs than the control group (P<0.001), as well as a lower amount of sedatives (P<0.001).
Conclusion We concluded that perioperative use of dexmedetomidine in pediatric patients with pulmonary hypertension reduces the PASP throughout the operative and postoperative period.
American Psychological Association (APA)
Abd al-Hamid, Hadil M.& Abd al-Aziz, Mayy M.& Umar, Ahmad H. Ali. 2017. The effect of perioperative use of dexmedetomidine on pediatric patients with pulmonary hypertension undergoing congenital cardiac surgery. Ain Shams Journal of Anesthesiology،Vol. 10, no. 1, pp.10-14.
https://search.emarefa.net/detail/BIM-841237
Modern Language Association (MLA)
Abd al-Hamid, Hadil M.…[et al.]. The effect of perioperative use of dexmedetomidine on pediatric patients with pulmonary hypertension undergoing congenital cardiac surgery. Ain Shams Journal of Anesthesiology Vol. 10, no. 1 (Mar. 2017), pp.10-14.
https://search.emarefa.net/detail/BIM-841237
American Medical Association (AMA)
Abd al-Hamid, Hadil M.& Abd al-Aziz, Mayy M.& Umar, Ahmad H. Ali. The effect of perioperative use of dexmedetomidine on pediatric patients with pulmonary hypertension undergoing congenital cardiac surgery. Ain Shams Journal of Anesthesiology. 2017. Vol. 10, no. 1, pp.10-14.
https://search.emarefa.net/detail/BIM-841237
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 14
Record ID
BIM-841237