Detection of cholecystokinin and glucagon like peptide in small intestine of Awassi sheep

Abstract EN

The enter endocrine cells in small intestine of sheep secreting some hormones that play key roles in regulation of certain important organs.

The endocrine cells of GIT are generally divided into two types, the open and close type.The aim of this study was unveil the relative frequency and regional distribution of enteroendocrine cells in some portions of small intestine of the Awassi sheep, detecting by using immunohistochemistry techniques.

Specimens of small intestine from ten of both sexes with different ages of sheep Ovis aries were used.

The Immunohistochemistry technique formed using two types of hormones cholecystokinin (CCK-8) and glucagon like peptide (GLP-1).

Result of immune detection findings demonstrated that in part of small intestine (duodenum, jejunum and ileum) there is clearly expression of the CCK-8 and GLP-1 subset of cells along the villus and crypts.

The cells are contained gut hormones appeared to be either triangular or flask-like in shape.

I-cell which contain CCK-8 increase proximally of small intestine and decrease caudally, while L-cell which contain GLP-1 decrease proximally but increase caudally of small intestine