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Evaluation of the correlation of oxytocin plasma levels and metabolic syndrome biomarkers (leptin, adiponectin and resistin) in newly diagnosed type 2 diabetes patients in Jordan : a cross sectional study
Other Title(s)
تأثير مستوى هرمون (الأوكسيتوسين) في بلازما الدم على ظهور مؤشرات الاضطراب الأيضي (الليبتين، الأديبونيكتين و الريسيستين) في مرضى السكري 2 في الأردن : دراسة مسحية
Joint Authors
Akur, Amal
Boulatova, Nailah
Arif, Ayman
Mumani, Mundhir
Silawi, Rula
Bustanji, Yasir
Kasabri, Violet
Source
Jordan Journal of Pharmaceutical Sciences
Issue
Vol. 9, Issue 2 (31 Aug. 2016), pp.115-128, 14 p.
Publisher
University of Jordan Deanship of Academic Research (DAR)
Publication Date
2016-08-31
Country of Publication
Jordan
No. of Pages
14
Main Subjects
Abstract EN
Levels of oxytocin (OXT) hormone and inflammatory biomarkers (leptin, resistin and adiponectin) were measured in 166 plasma samples of Metabolic Syndrome (MS) patients (1) that visited the outpatients’ endocrinology clinics, Jordan University Hospital (JUH).
Patients were subdivided into two arms according to their glucose profile status, subjects with glucose profile disturbances and normoglycemic subjects.
MS biomarkers were significantly different (P<0.01) between study groups, mean OXT levels (ng/mL) were exceptionally higher (p<0.01) in MS-control group (2.25+0.85) than in MS-pre/T2DM group (1.20+0.50).
Conversely, in comparison to MS-controls; MS-pre/T2DM patients had significantly higher adipocytokines plasma levels; namely resistin was 13 times higher (ng/mL) (82.05+ 32.44 vs.
6.45+4.39); leptin two times higher (ng/mL) (42.43+30.44 vs.
22.76+14.19) and adiponectin was 3-fold higher (µg/mL) (6.869+1.082 vs.
1.97+0.606).
These findings were indicative for the potential pharmacologic benefit of this hormone in minimization of inflammatory markers chronic deleterious effect.
American Psychological Association (APA)
al-Nuaymi, Mais M.& Kasabri, Violet& Akur, Amal& Boulatova, Nailah& Arif, Ayman& Mumani, Mundhir…[et al.]. 2016. Evaluation of the correlation of oxytocin plasma levels and metabolic syndrome biomarkers (leptin, adiponectin and resistin) in newly diagnosed type 2 diabetes patients in Jordan : a cross sectional study. Jordan Journal of Pharmaceutical Sciences،Vol. 9, no. 2, pp.115-128.
https://search.emarefa.net/detail/BIM-845829
Modern Language Association (MLA)
al-Nuaymi, Mais M.…[et al.]. Evaluation of the correlation of oxytocin plasma levels and metabolic syndrome biomarkers (leptin, adiponectin and resistin) in newly diagnosed type 2 diabetes patients in Jordan : a cross sectional study. Jordan Journal of Pharmaceutical Sciences Vol. 9, no. 2 (2016), pp.115-128.
https://search.emarefa.net/detail/BIM-845829
American Medical Association (AMA)
al-Nuaymi, Mais M.& Kasabri, Violet& Akur, Amal& Boulatova, Nailah& Arif, Ayman& Mumani, Mundhir…[et al.]. Evaluation of the correlation of oxytocin plasma levels and metabolic syndrome biomarkers (leptin, adiponectin and resistin) in newly diagnosed type 2 diabetes patients in Jordan : a cross sectional study. Jordan Journal of Pharmaceutical Sciences. 2016. Vol. 9, no. 2, pp.115-128.
https://search.emarefa.net/detail/BIM-845829
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 126-127
Record ID
BIM-845829