Immunological, cytogenetic and hepatoprotective effect of viola odorata Methanolic extract on methotrexate induced albino male mice
Other Title(s)
التأثير المناعي, الوراثي و التأثير الحامي للكبد للمستخلص الميثانولي لنبات ورد البنفسج Violoa odorata على ذكور الفئران البيض المستحثة بعقار الميثوتركسيت
Author
Source
Journal of Biotechnology Research Center
Issue
Vol. 11, Issue 2 (31 Dec. 2017), pp.47-55, 9 p.
Publisher
al-Nahrain University Biotechnology Research Center
Publication Date
2017-12-31
Country of Publication
Iraq
No. of Pages
9
Main Subjects
Abstract EN
Pants used in traditional medicine contain a vast array of substances that can be used to treat chronic and infectious diseases.
One of these medical plant Viola odorata which a popularly known as “Banafshah” and sweet violet in Asia and Europe respectively.
It is found in high altitudes of Himalyas, Europe and throughout North America.
The study was designed to assess immunological (total and differential count of white blood cells), cytogenetic (micronucleus formation) and hepatoprotective activity of methanolic extract of Viola odorata by using two doses 100 and 200mg/kg.
In addition, these effects were assessed after an interaction between the two doses of the plant and methtrexte drug.
Results:The results of this study indicated that Viola odorata had the ability to enhance immunity and reduced the frequency of micronucleus formation in bone marrow cells in addition to its hepatoprotective activity.
Alternatively, the plant was able to counteract the damage induced by methotrexate 40 mgkg.
American Psychological Association (APA)
Ibrahim, Ruqayah Muhammad. 2017. Immunological, cytogenetic and hepatoprotective effect of viola odorata Methanolic extract on methotrexate induced albino male mice. Journal of Biotechnology Research Center،Vol. 11, no. 2, pp.47-55.
https://search.emarefa.net/detail/BIM-846991
Modern Language Association (MLA)
Ibrahim, Ruqayah Muhammad. Immunological, cytogenetic and hepatoprotective effect of viola odorata Methanolic extract on methotrexate induced albino male mice. Journal of Biotechnology Research Center Vol. 11, no. 2 (Dec. 2017), pp.47-55.
https://search.emarefa.net/detail/BIM-846991
American Medical Association (AMA)
Ibrahim, Ruqayah Muhammad. Immunological, cytogenetic and hepatoprotective effect of viola odorata Methanolic extract on methotrexate induced albino male mice. Journal of Biotechnology Research Center. 2017. Vol. 11, no. 2, pp.47-55.
https://search.emarefa.net/detail/BIM-846991
Data Type
Journal Articles
Language
English
Notes
Record ID
BIM-846991