Ampicillin inhibition effect on HCT116 cell line
Other Title(s)
التأثير التثبيطي لعقار الامبيسيلين على نمو خلايا سرطان القولون HCT116
Joint Authors
Shakkaki, Zifaf Jasim Muhammad
al-Abbadi, Isra Najm Abd Allah
Source
Journal of al-Qadisiyah for Pure Science
Issue
Vol. 22, Issue 2 (30 Jun. 2017)6 p.
Publisher
al-Qadisiyah University College of Science
Publication Date
2017-06-30
Country of Publication
Iraq
No. of Pages
6
Main Subjects
Abstract EN
Ampicillin is a common antibiotic used treat infections derived by gram negative and positive bacteria.
The hypothesis of this work is to uncover the therapeutic action of Ampicillin in case of human colorectal carcinoma as a model of gastric malignancy in the presence or absence of bacterial toxin.
The results indicated that HCT116 viability was significantly attenuated by relatively high doses of Amp in presence or absence of LPS.
However LPS treatment alone of high impact on HCT116 cells growth.
We conclude that Ampicillin may have therapeutic effect on colorectal cancer upon and lower intestine bacterial infection.
Further studies required revealing Ampicillin effect on normal intestinal cells and underneath molecular mechanisms
American Psychological Association (APA)
Shakkaki, Zifaf Jasim Muhammad& al-Abbadi, Isra Najm Abd Allah. 2017. Ampicillin inhibition effect on HCT116 cell line. Journal of al-Qadisiyah for Pure Science،Vol. 22, no. 2.
https://search.emarefa.net/detail/BIM-850964
Modern Language Association (MLA)
Shakkaki, Zifaf Jasim Muhammad& al-Abbadi, Isra Najm Abd Allah. Ampicillin inhibition effect on HCT116 cell line. Journal of al-Qadisiyah for Pure Science Vol. 22, no. 2 (2017).
https://search.emarefa.net/detail/BIM-850964
American Medical Association (AMA)
Shakkaki, Zifaf Jasim Muhammad& al-Abbadi, Isra Najm Abd Allah. Ampicillin inhibition effect on HCT116 cell line. Journal of al-Qadisiyah for Pure Science. 2017. Vol. 22, no. 2.
https://search.emarefa.net/detail/BIM-850964
Data Type
Journal Articles
Language
English
Notes
Record ID
BIM-850964
