Three locally clays as a surfaces for adsorption of cephalexin monohydrate from aqueous solution : thermodynamic and desorption equilibrium
Joint Authors
al-Tawil, Saja S.
Isa, Sadun A.
al-Ani, Ramzi R.
Source
مجلة ابن الهيثم للعلوم الصرفة و التطبيقية
Publisher
University of Baghdad College of Education for Pure Science / Ibn al-Haitham
Publication Date
2017-12-31
Country of Publication
Iraq
No. of Pages
11
Main Subjects
English Abstract
The adsorption of cephalexin.H2O from aqueous solution on attapulgite, bentonite and kaolin has been studied at the human body temperature (37.5˚C) and at 5, 27, 47˚C in 0.1M hydrochloric acid (pH 1.2).
The value of pH 1.2 has been chosen to simulate the pH of stomach fluid.
The clays show the following order: Bentonite > attapulgite > kaolin, for their activity to adsorb cephalexin.H2O.
The charged clay particles can attract molecules either by electrostatic forces, for the molecules of oppositely charged, or by inducing dipole formation in the neutral molecule.
The L-shaped adsorption isotherm indicated that drug molecules arrangement in a flat geometry on the clay surface.
The results indicated the applicability of Langmuir isotherm for adsorption of drug on three clays.
The amount of cephalexin.H2O adsorbed on the three clays was increased with increasing pH value from 1.2 to 5.
At the acidic pH, the competition between cephalexin.H2O molecules and hydronium ions results in a reduction in adsorption process.
At fixed temperature and pH, the adsorption of cephalexin.H2O on the three clays was increased with increasing the ionic strength of solution.
The data showed a little increase in the amount of drug adsorbed by attapulgite and bentonite with increasing temperature, so the adsorption process appeared endothermic.
The reverse was observed with adsorption of cephalexin.H2O on kaolin surface (exothermic).
The extent of desorption of cephalexin.H2O from the clays increased when the concentration of drug increased.
This result may refer to the difficulty of desorption of the drug at low concentrations, which reflects a relatively higher adsorbate - adsorbent interaction
Data Type
Conference Papers
Record ID
BIM-851571
American Psychological Association (APA)
al-Tawil, Saja S.& Isa, Sadun A.& al-Ani, Ramzi R.. 2017-12-31. Three locally clays as a surfaces for adsorption of cephalexin monohydrate from aqueous solution : thermodynamic and desorption equilibrium. International Conference on Biology, Chemistry, Computer Science, Mathematics, and Physics, will take place (2017 : Ibn Al Haitham University of Baghdad, Iraq). . Special issue (2017), pp.195-205.Baghdad Iraq : University of Baghdad College of Education for Pure Science / Ibn al-Haitham.
https://search.emarefa.net/detail/BIM-851571
Modern Language Association (MLA)
al-Tawil, Saja S.…[et al.]. Three locally clays as a surfaces for adsorption of cephalexin monohydrate from aqueous solution : thermodynamic and desorption equilibrium. . Baghdad Iraq : University of Baghdad College of Education for Pure Science / Ibn al-Haitham. 2017-12-31.
https://search.emarefa.net/detail/BIM-851571
American Medical Association (AMA)
al-Tawil, Saja S.& Isa, Sadun A.& al-Ani, Ramzi R.. Three locally clays as a surfaces for adsorption of cephalexin monohydrate from aqueous solution : thermodynamic and desorption equilibrium. . International Conference on Biology, Chemistry, Computer Science, Mathematics, and Physics, will take place (2017 : Ibn Al Haitham University of Baghdad, Iraq).
https://search.emarefa.net/detail/BIM-851571
