Relationship between glycated haemoglobin and carotid atherosclerotic disease among patients with acute ischaemic stroke
Other Title(s)
العلاقة بين مستوى السكر التراكمي في الدم و مرض تصلب الشريان السباتي بين المرضى الذين يعانون من السكتة الدماغية الحادة
Joint Authors
al-Jafari, Danah
al-Bakr, Aishah
Nazish, Saima
Zafar, Azra
Shahid, Radwana
al-Khamis, Fahd Ahmad
al-Abdli, Majid
al-Sulayman, Abd Allah
al-Mulla, Faysal A.
Source
Sultan Qaboos University Medical Journal
Issue
Vol. 18, Issue 3 (31 Aug. 2018), pp.311-317, 7 p.
Publisher
Sultan Qaboos University College of Medicine and Health Sciences
Publication Date
2018-08-31
Country of Publication
Oman
No. of Pages
7
Main Subjects
Abstract EN
Objectives: This study aimed to determine the relationship between glycaemic control and carotid atherosclerotic disease among patients with acute ischaemic stroke (AIS).
Methods: This retrospective crosssectional study took place in the Neurology Department of King Fahad Hospital of University, Khobar, Saudi Arabia, from April to October 2017.
Data were collected from the medical records of 244 patients with a diagnosis of AIS confirmed by computed tomography.
Doppler ultrasounds of the carotid artery were performed to determine the presence of increased carotid intima media thickness (CIMT) and plaques.
Results: Significantly higher mean glycated haemoglobin (HbA1c) levels were noted in cases with high CIMT values (P = 0.002), but not in cases with carotid plaques (P = 0.360).
In addition, there was a significant association between diabetes mellitus (DM) and high CIMT (P = 0.045), but not with carotid plaques (P = 0.075).
Finally, while dyslipidaemia and age were independently correlated with high CIMT values (P = 0.034 and <0.001, respectively) and carotid plaques (P <0.001 each), no independent relationships were noted in terms of gender and other risk factors like DM, hypertension and smoking (P >0.050 each).
Conclusion: High HbA1c levels were associated with high CIMT values, but not with carotid plaques.
Therefore, HbA1c levels may be useful as an indirect marker of the initial stages of carotid artery atherosclerosis.
American Psychological Association (APA)
Nazish, Saima& Zafar, Azra& Shahid, Radwana& al-Bakr, Aishah& al-Khamis, Fahd Ahmad& al-Jafari, Danah…[et al.]. 2018. Relationship between glycated haemoglobin and carotid atherosclerotic disease among patients with acute ischaemic stroke. Sultan Qaboos University Medical Journal،Vol. 18, no. 3, pp.311-317.
https://search.emarefa.net/detail/BIM-852795
Modern Language Association (MLA)
Nazish, Saima…[et al.]. Relationship between glycated haemoglobin and carotid atherosclerotic disease among patients with acute ischaemic stroke. Sultan Qaboos University Medical Journal Vol. 18, no. 3 (Aug. 2018), pp.311-317.
https://search.emarefa.net/detail/BIM-852795
American Medical Association (AMA)
Nazish, Saima& Zafar, Azra& Shahid, Radwana& al-Bakr, Aishah& al-Khamis, Fahd Ahmad& al-Jafari, Danah…[et al.]. Relationship between glycated haemoglobin and carotid atherosclerotic disease among patients with acute ischaemic stroke. Sultan Qaboos University Medical Journal. 2018. Vol. 18, no. 3, pp.311-317.
https://search.emarefa.net/detail/BIM-852795
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 315-317
Record ID
BIM-852795