Histopathological effect of zinc oxide nanoparticles on kkidney and liver tissues in albino male mice

Abstract EN

Objective: The present study investigated the effects of different dose levels of Zinc oxide Nanoparticles (ZnO NPs) on the liver and kidney tissues in albino male mice.

Methadology: ZnO NPs was administrated as a daily oral dose of (150, 350 mg/kg body weight) gavage for 2 weeks.

Eighteen male mices were used by dividing them into three groups.

Result: Histopathological examination of kidney and hepatic tissues treated with ZnO NPs showed toxicity changes compared with control group.

Conclusion:This study demonstrated the ability of ZnO NPs to effect on kidney and liver tissues.

Recommendation: More study needed to know the effect of different doses of nanoparticles on human health.