Evaluation of platelets count, neutrophil to lymphocyte ratio and platelet to lymphocyte ratio in Syrian pregnant women with preeclampsia

Abstract EN

Objective : To assess the platelets count, neutrophil-tolymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) in patients with preeclampsia (PE), compared with pregnant women with hypertension and normal pregnant women in order to evaluate the association between preeclampsia and these parameters.

Methods : Forty nine pregnant women with preeclampsia, 22 pregnant women with hypertension and 50 healthy controls from an Obstetrics and Gynecology hospital in Damascus were prospectively evaluated.

The groups were compared in terms of clinical characteristics and hematological parameters.

Results : Platelets count decreased significantly (182.29 ± 64.97 x 109 / L, p = 0.01) in patients with preeclampsia as compared to the control group (215.86 ± 66.50 x 109 / L), while no difference of platelets count was observed between the control group and pregnant women with hypertension (209.09 ± 51.13 x109 / L, p = 0.67).

WBC count was significantly higher in pregnant women with preeclampsia (p < 0.01), while no significant difference was observed in women with hypertension (p = 0.31) compared with the healthy pregnant women.

No significant difference of the value of neutrophils, lymphocytes, NLR, and PLR was seen, whereas WBC count was high in women with preeclampsia.

Conclusions : NLR and PLR were not different between groups, while platelets count decreased in preeclampsia compared to normal pregnancy.

Platelets count may be a suitable marker in suspecting subjects with preeclampsia.