Primary plasma cell leukaemia : case report and review of the literature
Other Title(s)
سرطان خلية بلازما الدم الأولية : تقرير حالة و مراجعة الأدبيات
Joint Authors
Singh, Sarika
Yadav, Surekha
Rath, Ashutosh
Source
Sultan Qaboos University Medical Journal
Issue
Vol. 18, Issue 3 (31 Aug. 2018), pp.397-401, 5 p.
Publisher
Sultan Qaboos University College of Medicine and Health Sciences
Publication Date
2018-08-31
Country of Publication
Oman
No. of Pages
5
Main Subjects
Abstract EN
Plasma cell leukaemia (PCL) is one of the most aggressive and rarest forms of plasma cell dyscrasia.
However, the diagnostic criteria for this condition have not yet been revised and there is no specific treatment to significantly improve the course of the disease.
We report a 69-year-old male who presented to the Lok Nayak Hospital, New Delhi, India, in 2017 with dyspnoea and chest pain.
A peripheral blood smear showed an absolute plasma cell count of 2.16 × 109/L.
A bone marrow examination showed 61% atypical plasma cells exhibiting kappa light chain restriction.
Biochemical investigations were consistent with a diagnosis of primary PCL with renal involvement.
Bortezomib-based chemotherapy was initiated, which resulted in an improvement in the patient’s haematological and biochemical parameters.
This case report includes a comprehensive review of the clinical and diagnostic features, pathobiology and treatment of PCL.
American Psychological Association (APA)
Singh, Sarika& Rath, Ashutosh& Yadav, Surekha. 2018. Primary plasma cell leukaemia : case report and review of the literature. Sultan Qaboos University Medical Journal،Vol. 18, no. 3, pp.397-401.
https://search.emarefa.net/detail/BIM-853366
Modern Language Association (MLA)
Singh, Sarika…[et al.]. Primary plasma cell leukaemia : case report and review of the literature. Sultan Qaboos University Medical Journal Vol. 18, no. 3 (Aug. 2018), pp.397-401.
https://search.emarefa.net/detail/BIM-853366
American Medical Association (AMA)
Singh, Sarika& Rath, Ashutosh& Yadav, Surekha. Primary plasma cell leukaemia : case report and review of the literature. Sultan Qaboos University Medical Journal. 2018. Vol. 18, no. 3, pp.397-401.
https://search.emarefa.net/detail/BIM-853366
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 400-401
Record ID
BIM-853366