Impact of fetal diagnosis on neonates with congenital heart defects in the Kingdom of Bahrain

Abstract EN

Background and objectives: Fetal echocardiography is used for prenatal diagnosis of congenital cardiac malformations.

The impact on the neonatal outcomes in the Middle East remains unknown; therefore, the study aimed to determine the impact of fetal echocardiography on short- and intermediateterm postnatal outcomes.

Methods: This is a retrospective case-control study, including 35 infants with a prenatal diagnosis of congenital heart defects (CHD).

The cases were matched to 35 controls diagnosed postnatally with the same CHD.

Demographic, clinical, and procedural variables were collected on a pretested form and compared.

Statistical analysis was performed using SPSS 25.0.

Contingency tables were created, and the grouped data were compared using the Fisher’s exact test.

Results: Mean age at diagnosis in the prenatal and postnatal diagnosed group was 1 day and 12.58 days, respectively (P = 0.001).

In the prenatal group, 23 (65.71%) deliveries were performed in a tertiary healthcare setup compared to 13 (37.14%) in the postnatal group (P = 0.03).

Duct-dependent CHD requiring prostaglandins was observed in 13 (41.94%) neonates in the prenatal group compared to 9 (28.13%) in the postnatal group (P = 0.3).

There were 11 (31.43%) deaths in the prenatal group compared to 7 (20.00%) in the postnatal group (P = 0.4).

There were no statistically significant differences among the procedural variables.

Conclusion: Fetal echocardiography aided in identifying neonates with complex CHD resulting in better parental counseling and delivery at a tertiary care center.

However, this did not result in significantly short- and intermediate-term outcomes.

Due to the small sample size, future follow-up studies are encouraged