عوامل الاختطار عند مرضى الأورام البشروية غير الميلانينية

Abstract EN

Background & Objective: Non-melanotic skin cancers are common in the middle east region, including the Syrian Arab Republic.

They are preventable and detectable in early stages with increased patient education in the term of causative contributing factors.

Looking into the different types of non-melanotic skin tumors and their subtypes, and demonstrating the experience of the University Hospital for Skin and Venereal diseases, with the attempt of determining risk factors through linking them with the histological types having the worst prognosis.

In addition, determining the possibility of making a precise clinical diagnosis, leading consequently to early surgical intervention by excisional biopsy due to the lack of Moh's microscopic surgery technique.

Methods & Materials: this retrospective study was conducted by reviewing patients files in the hospital's central archives during the period from 2/1/2001 to 31/12/2011.

A total of 346918 patients have attended the hospital, and the number of patients with non-melanotic skin tumors was 3922.

Patient's files were studied to derive the available patients personal and demographic data.

Than dermatopathology archives were revised to ascertain histology and determine subtypes of various tumors.

Results: among the 3922 non-melanotic tumors, there were 1522 basal cell carcinomas, 546 squamous cell carcinomas, 13 mixed carcinomas, 1676 actinic keratoses, 33 cases of Bowen's disease and 132 oral leukoplakias.

The male to female ratio was 2.242:1, 2928 (74.655%) of tumors were located on the head, and the location on the head differed between males and females, the mixed carcinoma which has the poorest prognosis, were located on the head only.

The initial clinical diagnosis was correct in 2932 (74.757%) tumors.

Conclusion: it has been shown that the most effective risk factors were sun exposure, smoking, cosmetics and inappropriate dental prostheses.

Which leads us to emphasize on educational campaigning about avoidance of these risk factors