Cytotoxicity of imidacloprid and myclobutanil pesticides on three cancer cell lines

Joint Authors

Hammad, M. A.
Muhammad, Shayma M. S.
Ubayd, Najla M.
Abd al-Majid, Muhammad Ibrahim
Muhammad, K. A.

Source

Arab Universities Journal of Agricultural Sciences

Issue

Vol. 25, Issue 2 (31 Dec. 2017), pp.331-337, 7 p.

Publisher

Ain Shams University Faculty of Agriculture

Publication Date

2017-12-31

Country of Publication

Egypt

No. of Pages

7

Main Subjects

Medicine

Abstract EN

Three cancer cell lines, i.e.

hepg-2 (human liver carcinoma), mcf-7 (human breast adeno-carcinoma), and pc3 (prostatic small cell carci-noma) were used to determine the cytotoxic effects of the neonicotinoid insecticide (imidacloprid) and conazole fungicide (myclobutanil).

cytotoxicity was measured by neutral red incorporation (nri) as-say.

the lowest concentration of the tested pesti-cides (0.5 μg/ml) was toxic.

with the increase of the concentration up to 80 μg/ml, the department of plant protection, faculty of agric., ain shams university, shoubra elKheima, Cairo, Egypt department of genetics, faculty of agric., ain shams university, Cairo, Egypt damage degree of the cellular form and size was more serious.

the midpoint cytotoxicity value, (nri50) for imidacloprid and myclobutanil for hepg-2, mcf-7, and pc3 cancer cell lines were 110.5, 67.7 and 67.6 μg/ml and 38.12, 41 and 27.5 μg/ml, respectively.

in general, myclobutanil was very toxic in the three cancer cell lines compared with imidacloprid.

American Psychological Association (APA)

Muhammad, Shayma M. S.& Abd al-Majid, Muhammad Ibrahim& Muhammad, K. A.& Ubayd, Najla M.& Hammad, M. A.. 2017. Cytotoxicity of imidacloprid and myclobutanil pesticides on three cancer cell lines. Arab Universities Journal of Agricultural Sciences،Vol. 25, no. 2, pp.331-337.
https://search.emarefa.net/detail/BIM-879608

Modern Language Association (MLA)

Muhammad, Shayma M. S.…[et al.]. Cytotoxicity of imidacloprid and myclobutanil pesticides on three cancer cell lines. Arab Universities Journal of Agricultural Sciences Vol. 25, no. 2 (2017), pp.331-337.
https://search.emarefa.net/detail/BIM-879608

American Medical Association (AMA)

Muhammad, Shayma M. S.& Abd al-Majid, Muhammad Ibrahim& Muhammad, K. A.& Ubayd, Najla M.& Hammad, M. A.. Cytotoxicity of imidacloprid and myclobutanil pesticides on three cancer cell lines. Arab Universities Journal of Agricultural Sciences. 2017. Vol. 25, no. 2, pp.331-337.
https://search.emarefa.net/detail/BIM-879608

Data Type

Journal Articles

Language

English

Record ID

BIM-879608