Cytotoxicity of imidacloprid and myclobutanil pesticides on three cancer cell lines
Joint Authors
Hammad, M. A.
Muhammad, Shayma M. S.
Ubayd, Najla M.
Abd al-Majid, Muhammad Ibrahim
Muhammad, K. A.
Source
Arab Universities Journal of Agricultural Sciences
Issue
Vol. 25, Issue 2 (31 Dec. 2017), pp.331-337, 7 p.
Publisher
Ain Shams University Faculty of Agriculture
Publication Date
2017-12-31
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Three cancer cell lines, i.e.
hepg-2 (human liver carcinoma), mcf-7 (human breast adeno-carcinoma), and pc3 (prostatic small cell carci-noma) were used to determine the cytotoxic effects of the neonicotinoid insecticide (imidacloprid) and conazole fungicide (myclobutanil).
cytotoxicity was measured by neutral red incorporation (nri) as-say.
the lowest concentration of the tested pesti-cides (0.5 μg/ml) was toxic.
with the increase of the concentration up to 80 μg/ml, the department of plant protection, faculty of agric., ain shams university, shoubra elKheima, Cairo, Egypt department of genetics, faculty of agric., ain shams university, Cairo, Egypt damage degree of the cellular form and size was more serious.
the midpoint cytotoxicity value, (nri50) for imidacloprid and myclobutanil for hepg-2, mcf-7, and pc3 cancer cell lines were 110.5, 67.7 and 67.6 μg/ml and 38.12, 41 and 27.5 μg/ml, respectively.
in general, myclobutanil was very toxic in the three cancer cell lines compared with imidacloprid.
American Psychological Association (APA)
Muhammad, Shayma M. S.& Abd al-Majid, Muhammad Ibrahim& Muhammad, K. A.& Ubayd, Najla M.& Hammad, M. A.. 2017. Cytotoxicity of imidacloprid and myclobutanil pesticides on three cancer cell lines. Arab Universities Journal of Agricultural Sciences،Vol. 25, no. 2, pp.331-337.
https://search.emarefa.net/detail/BIM-879608
Modern Language Association (MLA)
Muhammad, Shayma M. S.…[et al.]. Cytotoxicity of imidacloprid and myclobutanil pesticides on three cancer cell lines. Arab Universities Journal of Agricultural Sciences Vol. 25, no. 2 (2017), pp.331-337.
https://search.emarefa.net/detail/BIM-879608
American Medical Association (AMA)
Muhammad, Shayma M. S.& Abd al-Majid, Muhammad Ibrahim& Muhammad, K. A.& Ubayd, Najla M.& Hammad, M. A.. Cytotoxicity of imidacloprid and myclobutanil pesticides on three cancer cell lines. Arab Universities Journal of Agricultural Sciences. 2017. Vol. 25, no. 2, pp.331-337.
https://search.emarefa.net/detail/BIM-879608
Data Type
Journal Articles
Language
English
Record ID
BIM-879608