Hematological and histological changes in mice fed aqueous extract of Senna ِalexandrina
Other Title(s)
التغيرات الدموية و النسجية في الفئران المعرضة للمستخلص المائي لنبات Senna alexandrina
Author
Source
Issue
Vol. 60, Issue 2 (30 Apr. 2019), pp.211-222, 12 p.
Publisher
University of Baghdad College of Science
Publication Date
2019-04-30
Country of Publication
Iraq
No. of Pages
12
Main Subjects
Abstract EN
This study aims to evaluate the effect of aqueous extract stem of dried of Senna Alexandr?a using male m?ce once daily at varying doses for 2 and weeks on hematological and histological changer in liver and kidney.
In the acute toxicity aqueous extracted of dried stem of Senna Alexandr?a were administrated orally to mice up to 20-25 gr of body weight, in sub-acute study mice was daily administrated orally with same extraction at dose 500,1000,2000 mg/kg for 14 days .
Hematological findings have shown in male group increase of RBC, HGB, HCT in increase of PIT in group treated with 500mg/ kg of body weight.
ncrease of PIT in group treated with 500mg/ kg of body weight.
Body weight was increase after application of extract at the dose of 1000 and 2000 mg/ kg .
The histology in liver includes congestion of central vein with inflammatory cell in their lamen, vascular dilation ,fatty infiltrations cytoplasmic vacillation necrotic hepatocyte .
Whereas in the kidney the changer includes shrunken glomeruli increasing of renal space, swelling and cytoplasmic vaculation of epithelial cells lining the renal tubule.
Increase in body weight was with a dose 1000,2000mg/kg week after 2 weeks.
American Psychological Association (APA)
al-Tai, Mustafa Abd al-Khaliq. 2019. Hematological and histological changes in mice fed aqueous extract of Senna ِalexandrina. Iraqi Journal of Science،Vol. 60, no. 2, pp.211-222.
https://search.emarefa.net/detail/BIM-880904
Modern Language Association (MLA)
al-Tai, Mustafa Abd al-Khaliq. Hematological and histological changes in mice fed aqueous extract of Senna ِalexandrina. Iraqi Journal of Science Vol. 60, no. 2 (2019), pp.211-222.
https://search.emarefa.net/detail/BIM-880904
American Medical Association (AMA)
al-Tai, Mustafa Abd al-Khaliq. Hematological and histological changes in mice fed aqueous extract of Senna ِalexandrina. Iraqi Journal of Science. 2019. Vol. 60, no. 2, pp.211-222.
https://search.emarefa.net/detail/BIM-880904
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 221-222
Record ID
BIM-880904