In vivo confocal microscopic analysis of keratitis induced by anaphylaxis to intravenous metronidazole : a case report and literature review
Joint Authors
Lu, Cheng Wei
Cui, Zhi Hua
Qi, Xiao Feng
Pant, Om Prakash
Lu, Cheng Bo
Hao, Ji Long
Zhou, Dan Dan
Source
Iranian Red Crescent Medical Journal
Issue
Vol. 21, Issue 1 (31 Jan. 2019), pp.1-5, 5 p.
Publisher
Publication Date
2019-01-31
Country of Publication
United Arab Emirates
No. of Pages
5
Main Subjects
Topics
Abstract EN
Introduction: Keratitis induced by type I hypersensitivity to metronidazole is rarely reported.
In vivo confocal microscopy (IVCM) is a promisingmethod for the investigation of cornealmorphology under pathological conditions.
The purpose of the present study was to investigate the IVCM features of keratitis associated with anaphylaxis to metronidazole and review the literature regarding IVCM application to study drug-related changes in the cornea.
Case Presentation: A 50-year-old woman with acute bilateral keratitis induced by anaphylaxis to intravenous metronidazole presented to the Department of Ophthalmology, the first affiliated hospital of Jilin University, Changchun, China in Jan 2018.
She initially experienced photophobia, moderate conjunctival injection, and watery discharge after infusion of intravenous metronidazole.
These symptoms gradually resolved one month after she was administered anti-allergic drugs.
Corneal morphology related to anaphylaxis to metronidazole was investigated by IVCM before and after treatment.
To our knowledge, this is the first reported case of IVCM images of keratitis associated with anaphylaxis to metronidazole.
Conclusions: In vivo confocal microscopy can allow objective evaluation of treatment response through cellular changes in the cornea and could provide good-quantity images of ocular surface tissues for follow-up
American Psychological Association (APA)
Lu, Cheng Wei& Cui, Zhi Hua& Qi, Xiao Feng& Pant, Om Prakash& Lu, Cheng Bo& Zhou, Dan Dan…[et al.]. 2019. In vivo confocal microscopic analysis of keratitis induced by anaphylaxis to intravenous metronidazole : a case report and literature review. Iranian Red Crescent Medical Journal،Vol. 21, no. 1, pp.1-5.
https://search.emarefa.net/detail/BIM-883641
Modern Language Association (MLA)
Lu, Cheng Wei…[et al.]. In vivo confocal microscopic analysis of keratitis induced by anaphylaxis to intravenous metronidazole : a case report and literature review. Iranian Red Crescent Medical Journal Vol. 21, no. 1 (Jan. 2019), pp.1-5.
https://search.emarefa.net/detail/BIM-883641
American Medical Association (AMA)
Lu, Cheng Wei& Cui, Zhi Hua& Qi, Xiao Feng& Pant, Om Prakash& Lu, Cheng Bo& Zhou, Dan Dan…[et al.]. In vivo confocal microscopic analysis of keratitis induced by anaphylaxis to intravenous metronidazole : a case report and literature review. Iranian Red Crescent Medical Journal. 2019. Vol. 21, no. 1, pp.1-5.
https://search.emarefa.net/detail/BIM-883641
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 4-5
Record ID
BIM-883641