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Ameliorative role of Ziziphus spina-christi leaf extracts against hepatic injury induced by Plasmodium chabaudi infected erythrocytes
Joint Authors
Diyab, Marwah S. M.
Dakhil, Muhammad A.
Mubaraki, Murad A.
Hafiz, Taghrid A.
al-Qurayshi, Salih
Source
Saudi Journal of Biological Sciences
Issue
Vol. 26, Issue 3 (31 Mar. 2019), pp.490-494, 5 p.
Publisher
Publication Date
2019-03-31
Country of Publication
Saudi Arabia
No. of Pages
5
Main Subjects
Topics
Abstract EN
One of the most common deadliest parasitic diseases is Malaria.
The biology and the pathogenesis of this fascinating parasite are not yet fully understood which make discovering effective alternative drugs a challenging task.
Moreover, the emergence of resistant strains added an additional burden in the journey of malaria elimination.
Traditional medicine used to be an alternative therapy choice owing to the presence of potent natural products.
Ziziphus spina-christi (L.) considered being one of the common potent natural plant in gulf region and other nations.
Therefore, this study designed to evaluate the ameliorative role of Z.
spina-christi leaf extracts (ZSCLE) against Plasmodium chabaudi-induced hepatic injury.
The study involved three groups were as follows; a vehicle control group, infected with 106 P.
chabaudiparasitized erythrocytes group and ZSCLE treated-infected mice with 106 P.
chabaudi-parasitized erythrocytes group.
The results showed a remarkable reduction of parasitemia level and notable reverse of the anemic picture among ZSCLE treated-infected mice.
The effects of ZSCLE on the liver functions enzymes and on the histopathological pictures of liver were significant.
It could be concluded that Z.
spina-christi leaf extracts have a protective role against Plasmodium infection that also marked through significant restoration of hepatic oxidative markers
American Psychological Association (APA)
Hafiz, Taghrid A.& Mubaraki, Murad A.& Diyab, Marwah S. M.& Dakhil, Muhammad A.& al-Qurayshi, Salih. 2019. Ameliorative role of Ziziphus spina-christi leaf extracts against hepatic injury induced by Plasmodium chabaudi infected erythrocytes. Saudi Journal of Biological Sciences،Vol. 26, no. 3, pp.490-494.
https://search.emarefa.net/detail/BIM-887229
Modern Language Association (MLA)
Hafiz, Taghrid A.…[et al.]. Ameliorative role of Ziziphus spina-christi leaf extracts against hepatic injury induced by Plasmodium chabaudi infected erythrocytes. Saudi Journal of Biological Sciences Vol. 26, no. 3 (Mar. 2019), pp.490-494.
https://search.emarefa.net/detail/BIM-887229
American Medical Association (AMA)
Hafiz, Taghrid A.& Mubaraki, Murad A.& Diyab, Marwah S. M.& Dakhil, Muhammad A.& al-Qurayshi, Salih. Ameliorative role of Ziziphus spina-christi leaf extracts against hepatic injury induced by Plasmodium chabaudi infected erythrocytes. Saudi Journal of Biological Sciences. 2019. Vol. 26, no. 3, pp.490-494.
https://search.emarefa.net/detail/BIM-887229
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 494
Record ID
BIM-887229