The first report on the in vitro antimicrobial activities of extracts of leaves of Ehretia serrata
Joint Authors
Abd al-Wahid
Chohan, Muhammad Mansha
Nasr Allah
Ahmad, Dildar
Source
Saudi Journal of Biological Sciences
Issue
Vol. 26, Issue 6 (30 Sep. 2019), pp.153-1261, 1109 p.
Publisher
Publication Date
2019-09-30
Country of Publication
Saudi Arabia
No. of Pages
1109
Main Subjects
Topics
Abstract EN
The increasing resistance of infectious microbial organisms to the existing arsenal of antibiotic drugs is on the rise.
There is a growing demand for the new antibiotics that are cost effective and easily available to the common people.
In search of new antimicrobial entities, this report deals with the in vitro antimicrobial activities of the crude extracts of leaves of Ehretia Serrata.
The methanolic extract and its sub-fractions namely n-hexane, chloroform, ethyl acetate, n-butanol and residual water fraction were screened against a range of 30 different bacterial strains and their zones of inhibition (ZI) and minimum inhibitory concentration (MIC) were subsequently evaluated.
Methanolic extract has shown activity against all the tested microorganisms such as Azospirillum lipoferum, Escherichia coli, Pseudomonas aeruginosa, Stenotrophomonas maltophilia and Enterococcus sp.
with ZOI ranged from 10.3 to 29.0 mm.
Moreover, the MIC values of methanolic extract and its sub-fractions against the tested bacteria ranged from 0.8 to 5.1 mg/mL.
GC–MS analysis of sub-fractions revealed the presence of mono (2-ethylexyl) 1,2-benzenedicarboxylate, diisooctyl-1,2-benzenedicarboxylate, 3,5-dehydro-6-methoxypivalate-cholest-22-ene-21-ol, and 3,5-bis (1,1-dimethylethyl)-4-hydroxybenzene-propanoic acid.
This is the first report on the in vitro antimicrobial activities of leaves of E.
Serrata.
American Psychological Association (APA)
Abd al-Wahid& Chohan, Muhammad Mansha& Ahmad, Dildar& Nasr Allah. 2019. The first report on the in vitro antimicrobial activities of extracts of leaves of Ehretia serrata. Saudi Journal of Biological Sciences،Vol. 26, no. 6, pp.153-1261.
https://search.emarefa.net/detail/BIM-889200
Modern Language Association (MLA)
Abd al-Wahid…[et al.]. The first report on the in vitro antimicrobial activities of extracts of leaves of Ehretia serrata. Saudi Journal of Biological Sciences Vol. 26, no. 6 (Sep. 2019), pp.153-1261.
https://search.emarefa.net/detail/BIM-889200
American Medical Association (AMA)
Abd al-Wahid& Chohan, Muhammad Mansha& Ahmad, Dildar& Nasr Allah. The first report on the in vitro antimicrobial activities of extracts of leaves of Ehretia serrata. Saudi Journal of Biological Sciences. 2019. Vol. 26, no. 6, pp.153-1261.
https://search.emarefa.net/detail/BIM-889200
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 1260-1261
Record ID
BIM-889200