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Epidemiology of antibiotic resistance in culture-positive hospitalized patients in selected hospitals in Khartoum, Sudan
Joint Authors
al-Amin, Najwa Muhammad
Uthman, Inas A.
al-Hasan, Lina
Abdalrahman, Ihab B.
Source
Sudan Journal of Medical Sciences
Issue
Vol. 14, Issue 1 (31 Mar. 2019), pp.15-23, 9 p.
Publisher
Omdurman Islamic University Faculty of Medicine
Publication Date
2019-03-31
Country of Publication
Sudan
No. of Pages
9
Main Subjects
Abstract EN
Objective: To study the prevelence of antibiotic resistance and the prevalent bacterial isolates in hospitalized patients in Khartoum hospitals.
Materials & Methods: A cross-sectional prevalence study was carried out during the period of April–November 2015 in Khartoum; 226 bacterial cultures were included.
Identification of isolates using standard biochemical tests and antibiotic susceptibilities were determined using disc diffusion method.
Results were interpreted according to the standards of the British society of antimicrobial chemotherapy.
Results: Eight bacterial species were isolated: Staphylococcus aureus, Enterococcus faecalis, Streptococcus spp., Klebsiella pneumoniae, Pseudomonas spp., Escherichia coli, Proteus spp., and Acinetobacter spp.
S.
aureus was the most prevalent, the majority of which were resistant to methicillin/oxacillin (MRSA).
Cultures in our study were mainly from urine (36.7%), blood samples (37.2%), and wound cultures (19%).
More than 90% of the tested isolates were resistant to cefuroxime; 54% and 73.8% of Gram-positive and Gram-negative isolates, respectively, were resistant to ceftazidime.
Furthermore, there was a high meropenem resistance among Gram-negative isolates tested.
Multi-resistant Acinetobacter spp.
as well as vancomycin-resistant S.
aureus was isolated.
Gram-negative isolates showed good susceptibilities to aminoglycosides as well as ciprofloxacin.
However, the high resistance rate to these antibiotics was observed in Gram-positive isolates in these hospitals.
Conclusion: Methicillin-resistant S.
aureus was the most prevalent organism.
Gramnegative isolates showed good susceptibilities to aminoglycosides and ciprofloxacin.
There were high resistance rates to cefuroxime, ceftazidime, and meropenem.
Five vancomycin-resistant S.
aureus were identified.
American Psychological Association (APA)
al-Amin, Najwa Muhammad& Uthman, Inas A.& al-Hasan, Lina& Abdalrahman, Ihab B.. 2019. Epidemiology of antibiotic resistance in culture-positive hospitalized patients in selected hospitals in Khartoum, Sudan. Sudan Journal of Medical Sciences،Vol. 14, no. 1, pp.15-23.
https://search.emarefa.net/detail/BIM-890735
Modern Language Association (MLA)
al-Amin, Najwa Muhammad…[et al.]. Epidemiology of antibiotic resistance in culture-positive hospitalized patients in selected hospitals in Khartoum, Sudan. Sudan Journal of Medical Sciences Vol. 14, no. 1 (2019), pp.15-23.
https://search.emarefa.net/detail/BIM-890735
American Medical Association (AMA)
al-Amin, Najwa Muhammad& Uthman, Inas A.& al-Hasan, Lina& Abdalrahman, Ihab B.. Epidemiology of antibiotic resistance in culture-positive hospitalized patients in selected hospitals in Khartoum, Sudan. Sudan Journal of Medical Sciences. 2019. Vol. 14, no. 1, pp.15-23.
https://search.emarefa.net/detail/BIM-890735
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 21-23
Record ID
BIM-890735