Effect of aqueous extract cyperus rotundus tubers as antioxidant on liver and kidney functions in albino males rats exposed to cadmium chloride toxi
Other Title(s)
تأثير المستخلص المائي لدرنات نبات السعد Cyperus rotundus كمضاد للاكسدة في وظائف الكبد و الكلى لذكور الجرذان البيض المعرضة للتسمم بكلوريد الكادميوم
Joint Authors
al-Dulaymi, Adnan Muhammad Ahmid
Husayn, Firyal Faruq
Source
Issue
Vol. 16, Issue 2 (30 Jun. 2019), pp.315-322, 8 p.
Publisher
University of Baghdad College of Science for Women
Publication Date
2019-06-30
Country of Publication
Iraq
No. of Pages
8
Main Subjects
Topics
- Liver
- Physiological effects
- Kidneys
- Plant extracts
- Poisoning
- Cadmium chlorideكلوريد الكادميوم
- Function tests(Medicine)
Abstract EN
The experiment was conducted in two stages: first stage: determination of the most effective dose of Cyperus rotundus tubers aquatic extract in male rats for 5 days, which was concentrated as (200 mg/kg body weight).
The second stage was designed to observe and test the protective effects of C.
rotundus tubers aquatic extract in the liver and kidney functions of male rats exposed to cadmium chloride poisoning (5 mg/kg bw) for 30 days.
The animals were divided into (4) groups within each group (5) animals weighted (200-220g).
The results of oral dose of cadmium chloride showed a significant increase of (P ˂ 0.05) in the activity of both enzymes Alanine aminotransferase (ALT), Aspartate aminotransferase (AST), Alkaline phosphatase (ALP), glucose, urea, uric acid, creatinine, malondialdehyde (MDA) and peroxynitrite (ONOO-).
And a significant decrease (P ˂ 0.05) in the values of total protein, albumin, globulin and glutathione (GSH) compared with the control group.
The oral dosage of the C.
rotundus tubers aquatic extract resulted in a significant increase in GSH.
The values of each were not significantly different ALT, AST, ALP, Glucose, urea, uric acid, creatinine, total protein, albumin, globulin, MDA and peroxy nitrite Compare with control group.
The results of the oral dosage with (C.
rotundus tubers aquatic extract + cadmium chloride) showed a positive effect on these values compared with the control group and cadmium chloride.
It is concluded that the C.
rotundus tubers aquatic extract has protective effects and reduces the effects that cadmium chloride can cause in rats liver and kidney functions through its antioxidant activity and removal of free radicals.
American Psychological Association (APA)
al-Dulaymi, Adnan Muhammad Ahmid& Husayn, Firyal Faruq. 2019. Effect of aqueous extract cyperus rotundus tubers as antioxidant on liver and kidney functions in albino males rats exposed to cadmium chloride toxi. Baghdad Science Journal،Vol. 16, no. 2, pp.315-322.
https://search.emarefa.net/detail/BIM-890867
Modern Language Association (MLA)
al-Dulaymi, Adnan Muhammad Ahmid& Husayn, Firyal Faruq. Effect of aqueous extract cyperus rotundus tubers as antioxidant on liver and kidney functions in albino males rats exposed to cadmium chloride toxi. Baghdad Science Journal Vol. 16, no. 2 (2019), pp.315-322.
https://search.emarefa.net/detail/BIM-890867
American Medical Association (AMA)
al-Dulaymi, Adnan Muhammad Ahmid& Husayn, Firyal Faruq. Effect of aqueous extract cyperus rotundus tubers as antioxidant on liver and kidney functions in albino males rats exposed to cadmium chloride toxi. Baghdad Science Journal. 2019. Vol. 16, no. 2, pp.315-322.
https://search.emarefa.net/detail/BIM-890867
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 320-322
Record ID
BIM-890867