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New fluorometric method for the determination of ketotifen fumarate using continuous flow injection analysis via ISNAG-fluorimeter
Other Title(s)
طريقة فلورة جديدة لتقدير كيتوتيفين فيوماريت باستخدام تقنية الحقن الجرياني المستمر بوساطة مقياس الفلورة ISNAG
Joint Authors
Munshid, Haydar Qays
Turki, Nagham Shakir
Source
Issue
Vol. 16, Issue 2 (30 Jun. 2019), pp.353-360, 8 p.
Publisher
University of Baghdad College of Science for Women
Publication Date
2019-06-30
Country of Publication
Iraq
No. of Pages
8
Main Subjects
Topics
Abstract EN
A newly developed analytical method was conducted for the determination of Ketotifen fumarate (KTF) in pharmaceuticals drugs via quenching of continuous fluorescence of 9(10H)-Acridone (ACD).
The method was applied using flow injection system of a new homemade ISNAG fluorimeter with fluorescence measurements at ± 90◦ via 2 × 4 solar cell.
The calibration graph was linear in the range of 1-45 mmol / L, with correlation coefficient r = 0.9762 and the limit of detection 29.785 μg /sample from the stepwise dilution for the minimum concentration in the linear dynamic ranged of the calibration graph.
The method was successfully applied to the determination of Ketotifen fumarate in two different pharmaceutical drugs.
A comparison was made between the newly developed method analysis and the classical method using the standard addition method via the use of individual and paired t-test and F-test.
It was noticed that there was no significant difference between the two methods at 95 % confidence level.
American Psychological Association (APA)
Turki, Nagham Shakir& Munshid, Haydar Qays. 2019. New fluorometric method for the determination of ketotifen fumarate using continuous flow injection analysis via ISNAG-fluorimeter. Baghdad Science Journal،Vol. 16, no. 2, pp.353-360.
https://search.emarefa.net/detail/BIM-890879
Modern Language Association (MLA)
Turki, Nagham Shakir& Munshid, Haydar Qays. New fluorometric method for the determination of ketotifen fumarate using continuous flow injection analysis via ISNAG-fluorimeter. Baghdad Science Journal Vol. 16, no. 2 (2019), pp.353-360.
https://search.emarefa.net/detail/BIM-890879
American Medical Association (AMA)
Turki, Nagham Shakir& Munshid, Haydar Qays. New fluorometric method for the determination of ketotifen fumarate using continuous flow injection analysis via ISNAG-fluorimeter. Baghdad Science Journal. 2019. Vol. 16, no. 2, pp.353-360.
https://search.emarefa.net/detail/BIM-890879
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 359
Record ID
BIM-890879