Effect of ginger (Zingiber Officinale)‎ on serum blood enzyme and lipid profile of female (Rattus Norvegicus)‎ rats treated with lead acetate

Abstract EN

The sub-lethal effects of lead on the liver enzyme (AST,ALT,ALP) and serum lipid profile parameters in the female rats, and the curative capacity of ginger(Zingiber officinale) were investigated .

Twenty four adult female rats were divided into four equal groups.

Group 1 as the control, the animals received the vehicle of distilled water (D.W.).

Group 2 received lead acetate (I.P) (10mg/ kg b.w.).

Group 3, animals drenched orally (100mg/ kg b.w.) of ginger.

Group 4 has been taken (I.P) (10mg/ kg b.w.) of lead acetate in combination with ginger orally/day (100mg/kg b.w.).

Weights of all animals at the first and the end of experiment were determined.

Rats from all groups were sacrificed at the end of experiment (2 weeks).

The study were showed that the weight of the animals was significantly decreased (p<0.05) in lead acetate group in comparison to other groups.

The results were appeared that lead acetate induced toxicity a significant rise in Triglycerides level, and asignificant lower in glucose level.

While did not significant changes in (AST, ALT, ALP and Cholestrol) in spite of there is different in thear means in comparison to control group.