Clinical and histopathological features of ovarian cancer in rizgary Hospital-Erbil city from 2014 to 2017

Abstract EN

Background: Ovarian cancer is a heterogeneous disease with variations in clinical behavior and outcome.

It is a group of many subtypes with distinct biological features that lead to differences in response to treatments, recurrence rates, and survival.

Objective: The aim of the study is to describe the epidemiology of the diagnosed cases of ovarian cancer from 2014 to 2017 in Erbil, Iraq.

Materials and Methods: This is a retrospective study, 100 ovarian cancer cases were reviewed from Rizgary Oncology Center in Erbil.

Then, we compared histological types with age groups of the study as premenopausal and postmenopausal, stage of the disease, grade, and with side of tumor.

Furthermore, this study includes the most important risk factors that may affect the incidence of ovarian cancer which includes menarche age, age of menopause, and with obesity.

Results: The result showed that ovarian cancer occurs in old age groups with a percentage of 64%.

The most common type is epithelial ovarian cancer with subtype papillary serous adenocarcinoma in 56%, with all types, the most affected site is the right one in a percent of 57%.

Grade 3 is the dominant one at presentation in a percent of 49%.

About staging at the time of diagnosis, Stage 4 presented in a percent of 58%, and 16% of patients were obese.

Conclusion: Most common type of cancer is epithelial type of papillary serous cystadenocarcinoma histology that occur in old patients and presented in advanced stage at the time of diagnosis with poor differentiation, and the most effective treatment is total abdominal hysterectomy + bilateral salpingo‑oophorectomy followed by adjuvant platinum‑based chemotherapy.