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Performance of ketamine as a general anesthetic for domestic fowl
Joint Authors
al-Awni, al-Sayyid E.
Sanhouri, Ahmad A.
Makki, Inam A. M.
Dayf Allah, Roaa A.
al-Doud, Mujahid Id
Yasin, Muhannad A.
Source
Sudan Journal of Science and Technology
Issue
Vol. 20, Issue 1 (30 Jun. 2019), pp.64-68, 5 p.
Publisher
Sudan University of Science and Technology Deanship of Scientific Research
Publication Date
2019-06-30
Country of Publication
Sudan
No. of Pages
5
Main Subjects
Abstract EN
Ketamine hydrochloride was tested as a general anesthetic administered as a single intramuscular injection at doses of 20, 30, 60, 175 or 350 mg/kg to 40-dayold male White Leghorn chickens.
Doses of 175 or 350 mg/kg are lethal to these birds.
Toxicity of the drug was expressed by the formula y = 0.984x + 1.72 using probit analysis with LD50 and LD99 values at 49.07 and 98.86 mg/kg, respectively.
The ED50 was 1.67 mg/kg .The therapeutic index (TI) was 29.38.indicating a wide margin of drug safety.
The time for onset of anesthesia was 1-10.7 min depending upon dose levels with drug dose and response being negatively correlated (y = - 4.85x + 13.933).
Stable anesthesia was maintained for 20-60 min with mean recovery time of 43.6, 42.4 and 35 min in the groups treated at 20, 30 or 60 mg/kg, respectively.
Differences between groups, however, were not significant (p > 0.05) when scores for individual birds were analyzed.
No untoward effects were observed up to 3 weeks when the experiments were terminated.
It is proposed that Ketamine, when given intramuscularly, has the potential to be used effectively and safely as a general anesthetic for domestic fowl.
American Psychological Association (APA)
al-Awni, al-Sayyid E.& Sanhouri, Ahmad A.& Makki, Inam A. M.& Dayf Allah, Roaa A.& al-Doud, Mujahid Id& Yasin, Muhannad A.. 2019. Performance of ketamine as a general anesthetic for domestic fowl. Sudan Journal of Science and Technology،Vol. 20, no. 1, pp.64-68.
https://search.emarefa.net/detail/BIM-892896
Modern Language Association (MLA)
al-Awni, al-Sayyid E.…[et al.]. Performance of ketamine as a general anesthetic for domestic fowl. Sudan Journal of Science and Technology Vol. 20, no. 1 (Jun. 2019), pp.64-68.
https://search.emarefa.net/detail/BIM-892896
American Medical Association (AMA)
al-Awni, al-Sayyid E.& Sanhouri, Ahmad A.& Makki, Inam A. M.& Dayf Allah, Roaa A.& al-Doud, Mujahid Id& Yasin, Muhannad A.. Performance of ketamine as a general anesthetic for domestic fowl. Sudan Journal of Science and Technology. 2019. Vol. 20, no. 1, pp.64-68.
https://search.emarefa.net/detail/BIM-892896
Data Type
Journal Articles
Language
English
Notes
Text in English ; abstracts in .
Record ID
BIM-892896