Experimental study of drug delivery system for prednisolone loaded and released by Mesoporous Silica MCM-41
Other Title(s)
دراسة تجريبية لنظام توصيل دواء البريدنيزولون المحمل و المحرر من قبل السليكا MCM-41
Joint Authors
Jassam, Abd al-Qadir Abd al-Amir
al-Bayati, Talib Muhammad Nayif
Source
al-Khwarizmi Engineering Journal
Issue
Vol. 15, Issue 1 (31 Mar. 2019), pp.117-124, 8 p.
Publisher
University of Baghdad al-Khwarizmi College of Engineering
Publication Date
2019-03-31
Country of Publication
Iraq
No. of Pages
8
Main Subjects
Topics
Abstract EN
In the present study, nanoporous material type MCM-41 was prepared by the sol-gel technique and was used as a carrier for prednisolone (PRD) drug delivery.
The structural properties of mesoporous were fully characterized by X-ray diffraction (XRD), N2 adsorption /desorption and Fourier-transform infrared (FTIR).
The mass transfer in term of adsorption process (loading) and desorption process (releasing) properties were investigated.
The maximum drug loading efficiency was equal to 38% and 47.5% at different concentrations.
The PRD released was prudently studied in water media of pH 6.8 simulated body fluid (SBF) in according to "United State Pharmacopeia (USP38)".
The results proved that the release of prednisolone from MCM-41 was (69.4%) after 24 hr.
The data of the released PRD was found to be submitted to a Korsmeyer–Peppas model.
American Psychological Association (APA)
al-Bayati, Talib Muhammad Nayif& Jassam, Abd al-Qadir Abd al-Amir. 2019. Experimental study of drug delivery system for prednisolone loaded and released by Mesoporous Silica MCM-41. al-Khwarizmi Engineering Journal،Vol. 15, no. 1, pp.117-124.
https://search.emarefa.net/detail/BIM-893127
Modern Language Association (MLA)
al-Bayati, Talib Muhammad Nayif& Jassam, Abd al-Qadir Abd al-Amir. Experimental study of drug delivery system for prednisolone loaded and released by Mesoporous Silica MCM-41. al-Khwarizmi Engineering Journal Vol. 15, no. 1 (Mar. 2019), pp.117-124.
https://search.emarefa.net/detail/BIM-893127
American Medical Association (AMA)
al-Bayati, Talib Muhammad Nayif& Jassam, Abd al-Qadir Abd al-Amir. Experimental study of drug delivery system for prednisolone loaded and released by Mesoporous Silica MCM-41. al-Khwarizmi Engineering Journal. 2019. Vol. 15, no. 1, pp.117-124.
https://search.emarefa.net/detail/BIM-893127
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 122-123
Record ID
BIM-893127