![](/images/graphics-bg.png)
Effect of leptin receptor polymorphism on Egyptian children with Entamoeba Histolytica infection
Joint Authors
Yahya, Rida S.
Hamid, Iman
Awwad, Suha I.
Source
Journal of the Egyptian Society of Parasitology
Issue
Vol. 49, Issue 2 (31 Aug. 2019), pp.277-282, 6 p.
Publisher
The Egyptian Society of Parasitology
Publication Date
2019-08-31
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Entamoeba histolytica is a protozoan parasite that causes amebic colitis, an invasive disease responsible for as many as 100,000 deaths per year globally.
Leptin signaling protects from amebiasis, with query molecular mechanism.
This study aimed to evaluate the effect of leptin Receptor Q223R Polymorphism on Egyptian children with Entamoeba histolytica infection.
After ethical clearance, blood and fecal samples were taken from one hundred children with E.
histolytica and 100 children as control group.
All children were subjected to anthropometric assessment.
Entamoeba infected group was further assessed for severity of symptoms, cyst load, and ELISA for differentiation of E.
histolytica from E.
dispar.
Q223R LEPR polymorphism then performed for both groups.
RR was higher in children with E.
histolytica group while QQ and QR were higher in control group.
Heavy cyst count, severe underweight, severe symptoms, and median leptin level was higher in RR group compared to QQ & QR groups.
The highest risk of R allele was severe underweight, severe symptoms and high leptin level
American Psychological Association (APA)
Awwad, Suha I.& Yahya, Rida S.& Hamid, Iman. 2019. Effect of leptin receptor polymorphism on Egyptian children with Entamoeba Histolytica infection. Journal of the Egyptian Society of Parasitology،Vol. 49, no. 2, pp.277-282.
https://search.emarefa.net/detail/BIM-893252
Modern Language Association (MLA)
Awwad, Suha I.…[et al.]. Effect of leptin receptor polymorphism on Egyptian children with Entamoeba Histolytica infection. Journal of the Egyptian Society of Parasitology Vol. 49, no. 2 (Aug. 2019), pp.277-282.
https://search.emarefa.net/detail/BIM-893252
American Medical Association (AMA)
Awwad, Suha I.& Yahya, Rida S.& Hamid, Iman. Effect of leptin receptor polymorphism on Egyptian children with Entamoeba Histolytica infection. Journal of the Egyptian Society of Parasitology. 2019. Vol. 49, no. 2, pp.277-282.
https://search.emarefa.net/detail/BIM-893252
Data Type
Journal Articles
Language
English
Notes
Includes appendix : p. 282
Record ID
BIM-893252