The role of metformin in patients with primary hypothyroidism
Joint Authors
al-Lihibi, Khalid Ibrahim
Abd al-Rahman, Marwah Isam
al-Hargani, Anmar
Source
al-Kindy College Medical Journal
Issue
Vol. 15, Issue 1 (30 Jun. 2019), pp.79-85, 7 p.
Publisher
University of Baghdad al-Kindi College of Medicine
Publication Date
2019-06-30
Country of Publication
Iraq
No. of Pages
7
Main Subjects
Topics
Abstract EN
Background: Insulin resistance is present in 50% or more of patients with primary hypothyroidism.
Metformin can decrease TSH levels in these patients by a complex matter, this can be of great help in clinical practice.
Objective: This study was designed to evaluate the effect of metformin in reducing TSH levels in patients with primary hypothyroidism.
Methods: Hundred patients with primary hypothyroidism, 82 females, 18 males were included in this study, everyone was followed up for two months after adding metformin 850 mg twice daily in addition to thyroxin.
Results: 36 patients (36%) have a normal baseline TSH and no change after 2 months, 64 patients (64%)have a change in TSH either a decrease(49 patients ,79.56%) or an increase (15 patients , 23.44 % ).
Conclusion: Metformin therapy is highly effective in reducing TSH levels in patients with primary hypothyroidism.
Keywords: Primary hypothyroidism, insulin resistance, metformin.
Corresponding Address: *Consultant Physician and Endocrinologist, FRCP-Edin, CABM.
Specialized Center for Endocrinology and Diabetes, Baghdad.
GP Nuclear Medicine, Specialized Center for Endocrinology and Diabetes, Baghdad.
Senior Medical Oncologist, MD, UK, Baghdad Teaching Hospital.
American Psychological Association (APA)
al-Lihibi, Khalid Ibrahim& Abd al-Rahman, Marwah Isam& al-Hargani, Anmar. 2019. The role of metformin in patients with primary hypothyroidism. al-Kindy College Medical Journal،Vol. 15, no. 1, pp.79-85.
https://search.emarefa.net/detail/BIM-893608
Modern Language Association (MLA)
al-Lihibi, Khalid Ibrahim…[et al.]. The role of metformin in patients with primary hypothyroidism. al-Kindy College Medical Journal Vol. 15, no. 1 (2019), pp.79-85.
https://search.emarefa.net/detail/BIM-893608
American Medical Association (AMA)
al-Lihibi, Khalid Ibrahim& Abd al-Rahman, Marwah Isam& al-Hargani, Anmar. The role of metformin in patients with primary hypothyroidism. al-Kindy College Medical Journal. 2019. Vol. 15, no. 1, pp.79-85.
https://search.emarefa.net/detail/BIM-893608
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 84-85
Record ID
BIM-893608