Gadolinium deposition in tissue following multiple contrast enhanced MRI examinations
Other Title(s)
ترسب الجادولينيوم في الأنسجة بعد الخضوع المتعدد للتصوير بتقنية الرنين المغناطيسي المحسنة بالصبغة
Author
Source
Journal of Medical and Pharmaceutical Sciences
Issue
Vol. 3, Issue 1 (31 Mar. 2019), pp.33-48, 16 p.
Publisher
Publication Date
2019-03-31
Country of Publication
Palestine (Gaza Strip)
No. of Pages
16
Main Subjects
Topics
Abstract EN
Gadolinium-based contrast agents (GBCAs) were considered extremely safe since their introduction for clinically used in 1988.
However, in 2006, nephrogenic systemic fibrosis (NSF) was reported in patients with end-stage renal failure who were exposed to some GBCAs.
In 2014, gadolinium deposition was found to occur in the brain tissues of patients exposed to multiple GBCA studies.
This project aimed to review currently published studies regarding gadolinium accumulation in tissues after repeated GBCA administrations to identify and summarize the recent findings for this issue.
Six scientific databases were electronically searched for relevant studies between 2009 and July 2016.
The reference lists were also checked and tracked to find related articles.
Studies were evaluated for relevance either by scanning their title and abstracts or reading the full text.
The primary search yielded 1765 papers, which were then narrowed down to 14 studies that fulfilled the inclusion criteria.
Two more studies were found by manually searching the reference lists.
Of these, three studies assessed gadolinium retention in the brain tissues on animal models, while the remaining 13 were human research studies
American Psychological Association (APA)
Mazhari, Uthman Muhammad. 2019. Gadolinium deposition in tissue following multiple contrast enhanced MRI examinations. Journal of Medical and Pharmaceutical Sciences،Vol. 3, no. 1, pp.33-48.
https://search.emarefa.net/detail/BIM-893693
Modern Language Association (MLA)
Mazhari, Uthman Muhammad. Gadolinium deposition in tissue following multiple contrast enhanced MRI examinations. Journal of Medical and Pharmaceutical Sciences Vol. 3, no. 1 (Mar. 2019), pp.33-48.
https://search.emarefa.net/detail/BIM-893693
American Medical Association (AMA)
Mazhari, Uthman Muhammad. Gadolinium deposition in tissue following multiple contrast enhanced MRI examinations. Journal of Medical and Pharmaceutical Sciences. 2019. Vol. 3, no. 1, pp.33-48.
https://search.emarefa.net/detail/BIM-893693
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 44-47
Record ID
BIM-893693