Effect of clinical Klebsiella pneumoniae extracted melanin on some immune aspects in mice
Other Title(s)
تأثير الميلانين المستخلص من بكتريا Klebsiella pneumonia السريرية على بعض الدلائل المناعية في الفئران
Joint Authors
al-Ubaydi, Murawij Abd al-Sattar
Suud, Hanan Muhammad
Source
The Iraqi Journal of Agricultural Science
Issue
Vol. 50, Issue 1 (28 Feb. 2019), pp.352-358, 7 p.
Publisher
University of Baghdad College of Agriculture
Publication Date
2019-02-28
Country of Publication
Iraq
No. of Pages
7
Main Subjects
Topics
Abstract EN
Melanin is a pigmented material varies from yellow to black color dependent on the type of melanin.
Not all the microorganisms can produce this material, most industrial researchers are looked after about melanin that produced from environmental microorganisms and little is known about from pathogenic bacteria and its role in pathogenesis.
Therefore this study is aimed to focus on the role of melanin produces by one pathogenic bacteria(Klebsiella pneumoniae ) isolated from an infected wound on host immune responses.The results of this study showed, that the increasing melanin concentration leads to decrease in the phagocytic index.
and in vivo tests are done by using different concentration of extracted microbial melanin, These concentrations showed variable effects on tested cytokines( IL-1β , IL-12 , TNF-α , IL-10 , IFN-γ and IL-4) In conclusion, microbial melanin is act as virulence factor throughout suppress the most important pro-inflammatory cytokines and that squeal to counteract immune responses.
American Psychological Association (APA)
Suud, Hanan Muhammad& al-Ubaydi, Murawij Abd al-Sattar. 2019. Effect of clinical Klebsiella pneumoniae extracted melanin on some immune aspects in mice. The Iraqi Journal of Agricultural Science،Vol. 50, no. 1, pp.352-358.
https://search.emarefa.net/detail/BIM-894575
Modern Language Association (MLA)
Suud, Hanan Muhammad& al-Ubaydi, Murawij Abd al-Sattar. Effect of clinical Klebsiella pneumoniae extracted melanin on some immune aspects in mice. The Iraqi Journal of Agricultural Science Vol. 50, no. 1 (2019), pp.352-358.
https://search.emarefa.net/detail/BIM-894575
American Medical Association (AMA)
Suud, Hanan Muhammad& al-Ubaydi, Murawij Abd al-Sattar. Effect of clinical Klebsiella pneumoniae extracted melanin on some immune aspects in mice. The Iraqi Journal of Agricultural Science. 2019. Vol. 50, no. 1, pp.352-358.
https://search.emarefa.net/detail/BIM-894575
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 356-358
Record ID
BIM-894575