Synthesis and biological activity of some new nitrogenous heterocyclic compounds derived from azachalcone
Other Title(s)
تحضير و الفعالية البايولوجية لبعض المركبات الحلقية الغير المتجانسة الجديدة و المشتقة من الأزاجالكونات
Joint Authors
Ruf, Munirah Y.
Said, Shakir Mahmud
Source
Publisher
University of Mosul College of Science
Publication Date
2019-04-30
Country of Publication
Iraq
No. of Pages
10
Main Subjects
Topics
English Abstract
A series of heterocyclic compounds containing oxygen and nitrogen atoms, isoxazoline ІI(a-d) and another containing two nitrogen atoms, pyrazolinesІII(a-d) and phenylpyrazolines IV(a-d) were prepared by the reaction of a proper azachalcones І(a-d) with hydroxylaminehydrochloride, hydrazine hydrate or phenylhydrazine.
These heterocyclic compounds were characterized by 1H-NMR , CHN , IR and UV spectra in addition to their some physical properties.
Also, these prepared compounds were screened for their biological activities and a theoretical calculation which shows that the product IVa obtained from 1,2 – rout was energetically more stable by 1.3967 kcal/mole than that came from 1,4 – rout, thus the reaction proceed via 1,2 – addition.
Data Type
Conference Papers
Record ID
BIM-894922
American Psychological Association (APA)
Ruf, Munirah Y.& Said, Shakir Mahmud. 2019-04-30. Synthesis and biological activity of some new nitrogenous heterocyclic compounds derived from azachalcone. Growing Chemistry Science and its Application (3 : 2019 : Banghazi, Libya). . Vol. 28, no. 2 (Special issue) (2019), pp.37-46.Mosul Iraq : University of Mosul College of Science.
https://search.emarefa.net/detail/BIM-894922
Modern Language Association (MLA)
Ruf, Munirah Y.& Said, Shakir Mahmud. Synthesis and biological activity of some new nitrogenous heterocyclic compounds derived from azachalcone. . Mosul Iraq : University of Mosul College of Science. 2019-04-30.
https://search.emarefa.net/detail/BIM-894922
American Medical Association (AMA)
Ruf, Munirah Y.& Said, Shakir Mahmud. Synthesis and biological activity of some new nitrogenous heterocyclic compounds derived from azachalcone. . Growing Chemistry Science and its Application (3 : 2019 : Banghazi, Libya).
https://search.emarefa.net/detail/BIM-894922
