Spectrophotometric determination of mesalazine
Other Title(s)
التقدير الطيفي للميزالازين
Author
Source
Publisher
University of Mosul College of Science
Publication Date
2019-04-30
Country of Publication
Iraq
No. of Pages
8
Main Subjects
Topics
English Abstract
Mesalazine (MESA) is determined by a simple and rapid visible spectrophotometric method.
This method is depend on oxidative coupling reaction of mesalazine with histidine (HIS) in alkaline media using N-bromosuccinimide (NBS) as oxidizing agent to form a water soluble and stable product, that it has a maximum absorption at 459 nm.
Beer's law is followed in a concentration range of 50 to 750 μg /20ml (2.5-37.5 μg /ml) with a molar absorptivity of 3.3682×103 l.mol-1.
cm-1.
The recommended method has been successfully applied to the assay of MESA in pharmaceutical preparations.
Data Type
Conference Papers
Record ID
BIM-894987
American Psychological Association (APA)
al-Zakariyya, Safa A.. 2019-04-30. Spectrophotometric determination of mesalazine. Growing Chemistry Science and its Application (3 : 2019 : Banghazi, Libya). . Vol. 28, no. 2 (Special issue) (2019), pp.127-134.Mosul Iraq : University of Mosul College of Science.
https://search.emarefa.net/detail/BIM-894987
Modern Language Association (MLA)
al-Zakariyya, Safa A.. Spectrophotometric determination of mesalazine. . Mosul Iraq : University of Mosul College of Science. 2019-04-30.
https://search.emarefa.net/detail/BIM-894987
American Medical Association (AMA)
al-Zakariyya, Safa A.. Spectrophotometric determination of mesalazine. . Growing Chemistry Science and its Application (3 : 2019 : Banghazi, Libya).
https://search.emarefa.net/detail/BIM-894987
