Synthesis and characterization of some novel hydrazones of N-{11H-pyrido[2,1-b]quinazolin-11-one-9-yl} hydrazine
Other Title(s)
تحضير و تشخيص بعض الهيدرازونات الجديدة N-{H11-بيريدو [1, 2-b] لكوينازولين 11-اون-9-يل} هيدرازين
Joint Authors
Jamil, Rafid K.
Shit, Ata Allah M.
Source
Publisher
University of Mosul College of Science
Publication Date
2019-04-30
Country of Publication
Iraq
No. of Pages
11
Main Subjects
Topics
English Abstract
The 2-[(6-chloro-2-pyridyl) amino]benzoic acid (I) was synthesized viaUllmann-Goldberg coupling by reaction of anthranilic acid with2,6-dichloropyridine.
The compound (I) was cyclized by using poly phosphoric acid (PPA) to give 9-chloro-11H-pyrido[2,1-b]quinazolin-11-one (II).
The compound (II) reacted with hydrazine hydrate to give N-{11H-pyrido[2,1-b]quinazolin-11-one-9-yl} hydrazine (III).
The compound (III) reacted with various aromatic aldehydes to yield the hydrazones (IVa-p).
The reaction progress was followed by thin layer of chromatography (TLC).
The physical constants and Rf values were recorded.
The synthesized compounds were confirmed via the spectral data (UV,I.R,1H-NMR, 13C-NMR, mass spectra).
The possible fragmentation pattrene of GC/MS for the compounds (IVa) were investigated (IVh).
Data Type
Conference Papers
Record ID
BIM-894992
American Psychological Association (APA)
Shit, Ata Allah M.& Jamil, Rafid K.. 2019-04-30. Synthesis and characterization of some novel hydrazones of N-{11H-pyrido[2,1-b]quinazolin-11-one-9-yl} hydrazine. Growing Chemistry Science and its Application (3 : 2019 : Banghazi, Libya). . Vol. 28, no. 2 (Special issue) (2019), pp.135-145.Mosul Iraq : University of Mosul College of Science.
https://search.emarefa.net/detail/BIM-894992
Modern Language Association (MLA)
Shit, Ata Allah M.& Jamil, Rafid K.. Synthesis and characterization of some novel hydrazones of N-{11H-pyrido[2,1-b]quinazolin-11-one-9-yl} hydrazine. . Mosul Iraq : University of Mosul College of Science. 2019-04-30.
https://search.emarefa.net/detail/BIM-894992
American Medical Association (AMA)
Shit, Ata Allah M.& Jamil, Rafid K.. Synthesis and characterization of some novel hydrazones of N-{11H-pyrido[2,1-b]quinazolin-11-one-9-yl} hydrazine. . Growing Chemistry Science and its Application (3 : 2019 : Banghazi, Libya).
https://search.emarefa.net/detail/BIM-894992
