Serological study of human cytomegalovirus in thalassemia patients and blood donors and its relation to IL-6 in Kirkuk City

Other Title(s)

دراسة مصلية للفيروس المضخم للخلايا البشري في مرضى الثلاسيميا و متبرعي الدم و علاقته بالانترليوكن -6 في مدية كركوك

Joint Authors

Abbas, Nishtiman Ahmad
Zaman, Najat Abd al-Qadir

Source

Rafidain Journal of Science

Issue

Vol. 28, Issue 1 (28 Feb. 2019), pp.23-28, 6 p.

Publisher

University of Mosul College of Science

Publication Date

2019-02-28

Country of Publication

Iraq

No. of Pages

6

Main Subjects

Medicine

Topics

Abstract EN

The aim of this study was to determine the relationship of human cytomegalovirus in thalassemic patients and blood donors in relation to IL-6 in Kirkuk City through screening of antihuman cytomegalovirus IgM and IgG antibodies in the serum of thalassemic patients and blood donors by using ELISA technique to detect the IgG and IgM in blood samples.

Blood samples were collected from 200 thalassemic patients and 180 samples from blood donor.

The study revealed that the positive rates for HCMV-IgG , HCMV-IgM and both HCMV IgM/IgG were positive among 152(76.0%),14,(7.0%) and 3(1.5%) respectively.

The rates of HCMV antibodies among 180 blood donors HCMV-IgG was detected in 68 (37.77%), the seropositive for HCMV-IgM was 7(3.88%), while for both HCMV-IgG and HCMV-IgM was 4(2.22%).

The HCMV elaborate cellular and immune manipulation strategies to maintain the virus-host equilibrium and the human immune response by humeral and cellular immunity including some cytokines as IL-6, so the rates of increased serum IL-6 was high among most HCMV seropositive subjects enrolled in this study although the highest rate were within thalassemic patients.

American Psychological Association (APA)

Abbas, Nishtiman Ahmad& Zaman, Najat Abd al-Qadir. 2019. Serological study of human cytomegalovirus in thalassemia patients and blood donors and its relation to IL-6 in Kirkuk City. Rafidain Journal of Science،Vol. 28, no. 1, pp.23-28.
https://search.emarefa.net/detail/BIM-894998

Modern Language Association (MLA)

Abbas, Nishtiman Ahmad& Zaman, Najat Abd al-Qadir. Serological study of human cytomegalovirus in thalassemia patients and blood donors and its relation to IL-6 in Kirkuk City. Rafidain Journal of Science Vol. 28, no. 1 (2019), pp.23-28.
https://search.emarefa.net/detail/BIM-894998

American Medical Association (AMA)

Abbas, Nishtiman Ahmad& Zaman, Najat Abd al-Qadir. Serological study of human cytomegalovirus in thalassemia patients and blood donors and its relation to IL-6 in Kirkuk City. Rafidain Journal of Science. 2019. Vol. 28, no. 1, pp.23-28.
https://search.emarefa.net/detail/BIM-894998

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references : p. 27-28

Record ID

BIM-894998