Physiological and histological effects of broccoli on lead acetate induced hepatotoxicity in young male albino rats
Other Title(s)
التأثيرات الفسلجية و النسجية للبروكلي على السمية الكبدية المحدثة بخلات الرصاص في ذكور الجرذان البيض اليافعة
Joint Authors
Ahmad, Mahmud Uthman
Ibrahim, Majidah Nuri
Muhammad, Sulaf Mustafa
Source
Iraqi Journal of Veterinary Sciences
Issue
Vol. 33, Issue 1 (30 Jun. 2019), pp.21-26, 6 p.
Publisher
University of Mosul College of Veterinary Medicine
Publication Date
2019-06-30
Country of Publication
Iraq
No. of Pages
6
Main Subjects
Topics
Abstract EN
The aim of this study was to investigate the ameliorative effect of Broccoli against lead acetate (PbA) hepatotoxicity by some physiological and histological indicators.
The results showed that intraperitoneal (I.P.) injection by 12 mg/kg body weight of lead acetate once a week for 8 weeks led to an increase in the activity of Glutamate pyruvate transaminase (GPT), Glutamate oxaloacetate transaminase (GOT), Alkaline phosphatase (ALP), Acid phosphatase (ACP), Total serum protein (TP) and Total serum bilirubin (TSB).
Liver's histological sections of lead acetate injected rats showed infiltration of inflammatory cells with sinusoid dilation, necrosis, and apoptosis of Kupffer cells.
Broccoli has an ameliorative effect, that the physiological parameters and histological examination have been showed an improvement.
In conclusion, lead acetate produces hepatic disorder and the potential use of Broccoli as a source of natural antioxidants or nutraceuticals protects against lead acetate hepatic toxicity.
American Psychological Association (APA)
Muhammad, Sulaf Mustafa& Ibrahim, Majidah Nuri& Ahmad, Mahmud Uthman. 2019. Physiological and histological effects of broccoli on lead acetate induced hepatotoxicity in young male albino rats. Iraqi Journal of Veterinary Sciences،Vol. 33, no. 1, pp.21-26.
https://search.emarefa.net/detail/BIM-895228
Modern Language Association (MLA)
Muhammad, Sulaf Mustafa…[et al.]. Physiological and histological effects of broccoli on lead acetate induced hepatotoxicity in young male albino rats. Iraqi Journal of Veterinary Sciences Vol. 33, no. 1 (2019), pp.21-26.
https://search.emarefa.net/detail/BIM-895228
American Medical Association (AMA)
Muhammad, Sulaf Mustafa& Ibrahim, Majidah Nuri& Ahmad, Mahmud Uthman. Physiological and histological effects of broccoli on lead acetate induced hepatotoxicity in young male albino rats. Iraqi Journal of Veterinary Sciences. 2019. Vol. 33, no. 1, pp.21-26.
https://search.emarefa.net/detail/BIM-895228
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 25-26
Record ID
BIM-895228