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Study of relationship between zinc levels and fetus weight at term
Other Title(s)
دراسة العلاقة بين سوية الزنك و وزن الأجنة في نهاية الحمل
Joint Authors
Nawfal, Hamdi
Serio, Ali
al-Halabi, Marwan
Sakr, Amir al-Hajj
Source
Journal of the Arab Board of Health Specializations
Issue
Vol. 20, Issue 1 (31 Mar. 2019), pp.11-17, 7 p.
Publisher
The Arab Board of Health Specializations
Publication Date
2019-03-31
Country of Publication
Syria
No. of Pages
7
Main Subjects
Abstract EN
Objective: Prospective observational study about the relationship between zinc levels (maternal and fetal plasma and amniotic fluid levels and umbilical cord concentration) and fetal weight at term.
Methods: The study started screening a group of pregnant women in AUHOG and El-Shahbaa Medical Center of SARC, to determine zinc deficiency and to choose the candidate to the next part of study.
Inclusion criteria were fetuses of healthy mothers without any risk factor for LBW so we had 60 cases, all measurements was done at term during an elected CS before umbilical cord cut, hence we got simultaneously a sample from maternal and fetal blood, amniotic fluid, then we had a piece of umbilical cord, then the newborn was assessed fully.
Results: Zinc deficiency rate was 70.43% (324 out of 460 mothers), mean weight was 2921±517 g, mean value of maternal serum zinc was 0.274±0.057 μg/ml, whereas mean fetal serum zinc levels was 0.98±0.68 μg/ml, but zinc deficiency appear with severe maternal zinc deficiency, and mean zinc values in amniotic fluid was 5.9±2.58 μg/ml.
Considering the relationship between maternal serum zinc levels and birth weight we found a positive relation (r=0.87).
Considering the relationship between fetal serum zinc levels and birth weight we found a positive relation (r=0.73).
Considering the relationship between amniotic fluid zinc levels and birth weight we found a moderate positive relation (r=0.69).
Mean umbilical cord zinc concentration was 98.418±68.1 μg/g.
Considering the relationship between cord tissue zinc concentrations and birth weight we found a positive relation (r=0.90).
Odds ratio for LBW in mild to moderate maternal zinc levels was so low (0.6), and that means that it does not affect birth weight, whereas odds ratio for LBW in severe maternal zinc levels was very high (12.2) and that means that severe maternal zinc deficiency is a risk factor for LBW.
Conclusions: Zinc is one of the most important mineral elements for fetal growth and there is a direct relation between its maternal serum levels and fetal serum levels, amniotic fluid levels and umbilical cord tissue concentration, hence they are affected by severe maternal zinc deficiency (less than 0.18 μg/ml elevates LBW risk by 12 fold.
American Psychological Association (APA)
Nawfal, Hamdi& Serio, Ali& al-Halabi, Marwan& Sakr, Amir al-Hajj. 2019. Study of relationship between zinc levels and fetus weight at term. Journal of the Arab Board of Health Specializations،Vol. 20, no. 1, pp.11-17.
https://search.emarefa.net/detail/BIM-895327
Modern Language Association (MLA)
Nawfal, Hamdi…[et al.]. Study of relationship between zinc levels and fetus weight at term. Journal of the Arab Board of Health Specializations Vol. 20, no. 1 (2019), pp.11-17.
https://search.emarefa.net/detail/BIM-895327
American Medical Association (AMA)
Nawfal, Hamdi& Serio, Ali& al-Halabi, Marwan& Sakr, Amir al-Hajj. Study of relationship between zinc levels and fetus weight at term. Journal of the Arab Board of Health Specializations. 2019. Vol. 20, no. 1, pp.11-17.
https://search.emarefa.net/detail/BIM-895327
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 17
Record ID
BIM-895327