Protective effect of Silymarin against kidney injury induced by carbon tetrachloride in male rats
Other Title(s)
التأثير الوقائي للسلمارين ضد إصابة الكلى الناجم عن رباعي كلوريد الكربون في ذكور الجرذان
Joint Authors
Ahmad, Muyassar Abd Allah
Tayawi, Husayn Muhammad
Ibrahim, Muhammad Khalil
Source
Iraqi Journal of Veterinary Sciences
Issue
Vol. 33, Issue 1 (30 Jun. 2019), pp.127-130, 4 p.
Publisher
University of Mosul College of Veterinary Medicine
Publication Date
2019-06-30
Country of Publication
Iraq
No. of Pages
4
Main Subjects
Abstract EN
The herbal drugs have a protective effect for kidney function against chemical toxicity.
24 male rats divided into 4 groups and treated as following, control group administrated orally with 1ml/kg.
B.W physiological solution (0.9%), One dose Carbon Tetrachloride (CCl4) 3 ml/kg.
B.W, Silymarin 150 mg/kg.
B.W and Silymarin150 mg/kg.
B.W with CCl4 3 ml/kg.
B.W for 30 days.
Oxidative stress resulted by CCl4 caused increasing in Creatinine, Urea, total protein, Albumin, malondialdehyde (MDA) levels decreasing in Glutathione (GSH) and superoxide dismutase (SOD) levels in serum and congestion, degeneration and desquamation in kidney tissue.
We concluded that Silymarin showed protective effect via increasing GSH, decreasing creatinine, Urea, total protein and MDA levels in serum and protect kidney tissue in rats.
American Psychological Association (APA)
Ahmad, Muyassar Abd Allah& Tayawi, Husayn Muhammad& Ibrahim, Muhammad Khalil. 2019. Protective effect of Silymarin against kidney injury induced by carbon tetrachloride in male rats. Iraqi Journal of Veterinary Sciences،Vol. 33, no. 1, pp.127-130.
https://search.emarefa.net/detail/BIM-895490
Modern Language Association (MLA)
Ahmad, Muyassar Abd Allah…[et al.]. Protective effect of Silymarin against kidney injury induced by carbon tetrachloride in male rats. Iraqi Journal of Veterinary Sciences Vol. 33, no. 1 (2019), pp.127-130.
https://search.emarefa.net/detail/BIM-895490
American Medical Association (AMA)
Ahmad, Muyassar Abd Allah& Tayawi, Husayn Muhammad& Ibrahim, Muhammad Khalil. Protective effect of Silymarin against kidney injury induced by carbon tetrachloride in male rats. Iraqi Journal of Veterinary Sciences. 2019. Vol. 33, no. 1, pp.127-130.
https://search.emarefa.net/detail/BIM-895490
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 130
Record ID
BIM-895490