Reassessing the risks of MMR vaccination for egg-allergic patients referred by healthcare workers : a clinical paradigm
Joint Authors
Source
Iranian Red Crescent Medical Journal
Issue
Vol. 21, Issue 6 (30 Jun. 2019), pp.1-5, 5 p.
Publisher
Publication Date
2019-06-30
Country of Publication
United Arab Emirates
No. of Pages
5
Main Subjects
Sociology and Anthropology and Social Work
Topics
Abstract EN
Background: Egg allergy for the Measles-Mumps-Rubella (MMR) vaccine is still the cause of concern for many healthcare workers and families due to reactions such as anaphylaxis.
Objectives: This study aimed to reassess the risk of MMR vaccination in infants with egg allergy referred by healthcare workers.
Methods: This cross-sectional observational study was performed in a university-affiliated hospital in Istanbul, Turkey, between March 2017 and September 2018.
The study patients were one-year-old infants who were candidates for MMR vaccination, and referred to our outpatient allergy clinic by healthcare workers due to egg allergy.
The children were diagnosed with egg allergy by a pediatric allergist and then received the MMR vaccine.
Results: Among 50 children aged one year, 19 (38%) were female, and 31 (62%) were male.
The diagnosis was atopic dermatitis in 29 (58%) patients, urticaria in 18 (36%) patients, angioedema in 2 (4%) patients, and anaphylaxis in one (2%) patient.
Fourteen (28%) patients had both egg and cow’s milk allergy.
Four (8%) patients had egg, cow’s milk, and wheat allergy.
The total IgE level was 119.80 213.43 IU/mL.
Specific IgE levels for egg white were positive in 37 patients.
Specific IgE levels for egg white were 15.2629.64 kU/L.
Skin prick test results were positive for egg allergens in 35 patients with a mean diameter of 3.122.18mmfor egg yolk and 3.27 2.62 mm for egg white.
None of the patients with egg allergy developed anaphylactic reaction and only one patient had urticaria within 5 min after vaccination.
There was no correlation between specific IgE levels for egg white and diagnosis of the patients.
Conclusions: MMR vaccine administration to children with egg allergy is safe.
Life-threatening reactions to the MMR vaccine in patients with egg-allergy are very rare.
It seems in cases of hypersensitivity reactions such as acute anaphylaxis events, the MMR vaccine needs to be administered in a hospital under the supervision of a pediatric allergist.
American Psychological Association (APA)
Can, Ceren& Kural, Bahar. 2019. Reassessing the risks of MMR vaccination for egg-allergic patients referred by healthcare workers : a clinical paradigm. Iranian Red Crescent Medical Journal،Vol. 21, no. 6, pp.1-5.
https://search.emarefa.net/detail/BIM-895947
Modern Language Association (MLA)
Can, Ceren& Kural, Bahar. Reassessing the risks of MMR vaccination for egg-allergic patients referred by healthcare workers : a clinical paradigm. Iranian Red Crescent Medical Journal Vol. 21, no. 6 (Jun. 2019), pp.1-5.
https://search.emarefa.net/detail/BIM-895947
American Medical Association (AMA)
Can, Ceren& Kural, Bahar. Reassessing the risks of MMR vaccination for egg-allergic patients referred by healthcare workers : a clinical paradigm. Iranian Red Crescent Medical Journal. 2019. Vol. 21, no. 6, pp.1-5.
https://search.emarefa.net/detail/BIM-895947
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 4-5
Record ID
BIM-895947