Regression of renal angiomyolipomas with oral rapamycin therapy in a patient with tuberous sclerosis complex disease

Abstract EN

We present a case of a 32-year-old female who had been diagnosed tuberous sclerosis complex (TSC) two years ago.

In view of serious hemorrhagic complication risk of the selective embolization, we commenced her on oral rapamycin therapy for regression of angiomyolipomas (AMLs).

On the 1 st year of rapamycin treatment, bilateral renal AMLs were regressed and bilateral selective embolization of the AML was performed after the 1 st year of treatment.

Rapamycin therapy may regress renal lesions in TSC disease.

Therefore, it may increase surgical intervention.