Turner syndrome with hypertension

Abstract EN

A sixteen-year-old Bahraini female with a history of uncontrolled hypertension presented with amenorrhea for which ultrasound abdomen revealed rudimentary ovaries (streak gonads) with normal sized kidneys.

Laboratory and diagnostic data were all normal with a blood pressure of 180/95 mmHg.

However, 24-hour ambulatory BP monitor confirmed hypertension with an average BP of 177/100 mmHg.

The patient had normal IQ and a short stature with webbed neck, low-set ears with widely-spaced nipples and increased carrying angle; all these characteristics were typical of Turner syndrome.

A blood sample of the patient was sent for karyotype analysis which showed an abnormal karyotype with monosomy X, such as 45,X0[20%].

Chromosome analysis had confirmed the diagnosis of Turner syndrome which correlates with the other test results since over 50% of young females with Turner syndrome experience abnormal blood pressure similar to that of adult patients with secondary hypertension.