Miller-fisher syndrome : a variant of Guillain-Barre syndrome

Abstract EN

Guillain-Barre syndrome (GBS) is a rare neurological condition affecting all ages.

It is rare in pediatric population; the disease is preceded by viral or bacterial infection.

GBS present as a rapid onset ascending paralysis with pain and sensory impairment.

Miller Fisher syndrome is a rare but most recognized variant of GBS; it presents by the classical triad of symptoms: ataxic gait, absence of reflexes and ophthalmoplegia.

A healthy six-year-old boy, not known to have any medical illnesses, presented with the classical triad of symptoms after ten days’ history of gastroenteritis.

Ganglioside GQ1B (IgG, IgM) antibodies were markedly elevated and the patient was started immediately on intravenous immunoglobulin (IVIG).

After a few days, the patient showed marked improvement in gait with no further deterioration in clinical condition.