BK virus nephropathy in living donor renal allograft recipients : an observational study from a large transplant center in India
Joint Authors
Gupta, Ashwani K.
Malik, Manish
Gupta, Pallav
Gupta, Anurag
Bhargava, Vinant
Bhalla, A. K.
Rana, D. S.
Source
Saudi Journal of Kidney Diseases and Transplantation
Issue
Vol. 29, Issue 6 (31 Dec. 2018), pp.1366-1370, 5 p.
Publisher
Saudi Center for Organ Transplantation
Publication Date
2018-12-31
Country of Publication
Saudi Arabia
No. of Pages
5
Main Subjects
Abstract EN
BK virus is a polyoma virus which remains in latent phase in the urinary tract, particularly in the renal tubular epithelial cells.
In immunosuppressed patients, it is activated and manifests as tubule-interstitial nephritis causing renal allograft dysfunction.
A total of 402 patients who underwent renal allograft biopsy from 2013 to 2016 were included in this study; six patients were diagnosed to have BK virus nephropathy.
Histopathology showed ground glass intra-nuclear inclusions accompanied by acute tubular injury, interstitial inflammation, and varying degree of interstitial fibrosis and tubular atrophy.
Patients were managed with reduction in the overall immunosuppression.
Only one patient progressed to graft failure on follow-up.
The overall prevalence of polyoma virus at our center is 1.49%.
American Psychological Association (APA)
Gupta, Pallav& Gupta, Ashwani K.& Bhalla, A. K.& Malik, Manish& Gupta, Anurag& Bhargava, Vinant…[et al.]. 2018. BK virus nephropathy in living donor renal allograft recipients : an observational study from a large transplant center in India. Saudi Journal of Kidney Diseases and Transplantation،Vol. 29, no. 6, pp.1366-1370.
https://search.emarefa.net/detail/BIM-896409
Modern Language Association (MLA)
Gupta, Pallav…[et al.]. BK virus nephropathy in living donor renal allograft recipients : an observational study from a large transplant center in India. Saudi Journal of Kidney Diseases and Transplantation Vol. 29, no. 6 (Nov. / Dec. 2018), pp.1366-1370.
https://search.emarefa.net/detail/BIM-896409
American Medical Association (AMA)
Gupta, Pallav& Gupta, Ashwani K.& Bhalla, A. K.& Malik, Manish& Gupta, Anurag& Bhargava, Vinant…[et al.]. BK virus nephropathy in living donor renal allograft recipients : an observational study from a large transplant center in India. Saudi Journal of Kidney Diseases and Transplantation. 2018. Vol. 29, no. 6, pp.1366-1370.
https://search.emarefa.net/detail/BIM-896409
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 1369-1370
Record ID
BIM-896409