Pattern of glomerular disease and clinicopathological correlation : a single-center study from Eastern Nepal
Joint Authors
Sharma, Sanjib Kumar
Bartaula, Bijay
Subedi, Manish
Pant, Ashok R.
Adhikari, Purbesh
Source
Saudi Journal of Kidney Diseases and Transplantation
Issue
Vol. 29, Issue 6 (31 Dec. 2018), pp.1410-1416, 7 p.
Publisher
Saudi Center for Organ Transplantation
Publication Date
2018-12-31
Country of Publication
Saudi Arabia
No. of Pages
7
Main Subjects
Abstract EN
The pattern of glomerular disease varies worldwide.
In the absence of kidney disease/kidney biopsy registry in Nepal, the exact etiology of different forms of glomerular disease is primarily unknown in our country.
We analyzed 175 cases of renal biopsies performed from September 2014 to August 2016 in Internal Medicine Ward at B.P.
Koirala Institute of Health Sciences.
The most common indication for renal biopsy was nephrotic syndrome (34.9%), followed by systemic lupus erythematosus (SLE) with suspected renal involvement (22.3%).
Majority of patients were in the 30-60 years' bracket (57.2%), with the mean age of the patients being 35.37 years.
The average number of glomeruli per core was 13, with inadequate sampling in 5.1%.
Immunoglobulin A (IgA) nephropathy (17%) was found to be the most common primary glomerular disease, followed by membranous nephropathy (14.6%) and focal segmental glomerulosclerosis (14.6%).
The most common secondary glomerular disease was lupus nephritis (LN).
Complications associated with renal biopsy were pain at biopsy site in 18% of cases, hematuria in 6%, and perinephric hematoma in 4% cases.
Although the most common primary glomerular disease was IgA nephropathy, significantly higher population of SLE with LN among Nepalese in comparison with other developing countries warrants further evaluation.
As an initial attempt toward documentation of glomerular diseases in the national context, this study should serve as a stepping stone toward the eventual establishment of a full-fledged national registry of glomerular diseases in Nepal.
American Psychological Association (APA)
Subedi, Manish& Bartaula, Bijay& Pant, Ashok R.& Adhikari, Purbesh& Sharma, Sanjib Kumar. 2018. Pattern of glomerular disease and clinicopathological correlation : a single-center study from Eastern Nepal. Saudi Journal of Kidney Diseases and Transplantation،Vol. 29, no. 6, pp.1410-1416.
https://search.emarefa.net/detail/BIM-896436
Modern Language Association (MLA)
Subedi, Manish…[et al.]. Pattern of glomerular disease and clinicopathological correlation : a single-center study from Eastern Nepal. Saudi Journal of Kidney Diseases and Transplantation Vol. 29, no. 6 (Nov. / Dec. 2018), pp.1410-1416.
https://search.emarefa.net/detail/BIM-896436
American Medical Association (AMA)
Subedi, Manish& Bartaula, Bijay& Pant, Ashok R.& Adhikari, Purbesh& Sharma, Sanjib Kumar. Pattern of glomerular disease and clinicopathological correlation : a single-center study from Eastern Nepal. Saudi Journal of Kidney Diseases and Transplantation. 2018. Vol. 29, no. 6, pp.1410-1416.
https://search.emarefa.net/detail/BIM-896436
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 1415-1416
Record ID
BIM-896436