The impact of blood flow rate on dialysis dose and phosphate removal in hemodialysis patients
Joint Authors
Rafiq, Hisham
Atif, Tawfiq
al-Kabbaj, Driss
Source
Saudi Journal of Kidney Diseases and Transplantation
Issue
Vol. 29, Issue 4 (31 Aug. 2018), pp.872-878, 7 p.
Publisher
Saudi Center for Organ Transplantation
Publication Date
2018-08-31
Country of Publication
Saudi Arabia
No. of Pages
7
Main Subjects
Topics
Abstract EN
The inadequacy of dialysis and hyperphosphatemia are both associated with morbidity and mortality in chronic hemodialysis (HD) patients.
Blood flow rate (BFR) during HD is one of the important determinants of increasing dialysis dose.
The aim of this study was to determine the effect of increasing BFR on dialysis dose and phosphate removal.
Forty-four patients were included in a cross-sectional study.
Each patient received six consecutive dialysis sessions as follows: three consecutive sessions with a BFR of 250 mL/min, followed by three others with BFR of 350 mL/min without changing the other dialysis parameters.
Patients’ body weight was recorded, and blood samples (serum urea and phosphate) were collected before and after each dialysis session.
For assessing the efficacy of dialysis, urea reduction ratio (URR), Kt/VDiascan (Kt by Diascan and V by Watson), Kt/V Daugirdas (Daugirdas 2nd generation), equilibrated Kt/V, and phosphate reduction rate (PRR) were used.
The increase of BFR by 100 mL/min resulted in a significant increase of URR, Kt/VDiascan, Kt/VDaugirdas, equilibrated Kt/V, and PRR: URR; 75.41 ± 5.60; 83.51 ± 6.12; P <0.001), (Kt/VDiascan; 1.28 ± 0.25; 1.55 ± 0.15; P <0.001), (Kt/VDaugirdas; 1.55 ± 0.26; 2.10 ± 0.61; P = 0.001), equilibrated Kt/V; 1.40 ± 0.19; 1.91 ± 0.52; P = 0.001), and (PRR; 50.32 ± 12.22; 63.66 ± 13.10; P = 0.010).
Adequate dialysis, defined by single-pool Kt/V ≥1.4, was achieved using two different BFRs: 250 and 350 mL/min, respectively, in 73% and 100% of the cases.
Increasing the BFR by 40% is effective in increasing
American Psychological Association (APA)
Rafiq, Hisham& Atif, Tawfiq& al-Kabbaj, Driss. 2018. The impact of blood flow rate on dialysis dose and phosphate removal in hemodialysis patients. Saudi Journal of Kidney Diseases and Transplantation،Vol. 29, no. 4, pp.872-878.
https://search.emarefa.net/detail/BIM-896565
Modern Language Association (MLA)
Rafiq, Hisham…[et al.]. The impact of blood flow rate on dialysis dose and phosphate removal in hemodialysis patients. Saudi Journal of Kidney Diseases and Transplantation Vol. 29, no. 4 (Jul. / Aug. 2018), pp.872-878.
https://search.emarefa.net/detail/BIM-896565
American Medical Association (AMA)
Rafiq, Hisham& Atif, Tawfiq& al-Kabbaj, Driss. The impact of blood flow rate on dialysis dose and phosphate removal in hemodialysis patients. Saudi Journal of Kidney Diseases and Transplantation. 2018. Vol. 29, no. 4, pp.872-878.
https://search.emarefa.net/detail/BIM-896565
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 877-878
Record ID
BIM-896565