Fetal choroid plexus cyst : antenatal findings and clinical implications

Abstract EN

Objective: Study our experience with the choroid plexus cysts (CPC) in the cerebral lateral ventricles, the clinical implications and associations, for better counseling and follow up plan.

Methods: It is a retrospective study, conducted in Women’s Hospital, Hamad Medical Corporation, Doha, Qatar.

During the period from January 2015 till September 2017.

The data was collected from the ultrasound software and maternal records for the pregnancy progress, foetal complications, and neonatal outcome.

The data was kept in password protected Excel sheet (©2010 Microsoft Corporation).

The analysis was done using Wizard Statistical Software (version 1.9.13) with p-values of 0.05.

Results: Ninety one patients diagnosed with CPC during the period from January 2015 and September 2017.

Mean maternal age at diagnosis 33.2±1.4 years.

CPC was seen at the second trimester scan with mean gestational age of 18.6±0.53 weeks.

7.7% had associated brain anomalies, and 30% had associated non-brain anomalies, 9.9% had genetic diseases, 9.9% had an IUGR, and same for IUFD with a significant deference between isolated and associated CPC, (p-value <0.01).

19% was the rate for NICU admission with one neonatal death (due to trisomy 18).

Conclusions: Finding of CPC should alert the clinicians for comprehensive, detailed ultrasound examination in a specialized center.

Isolated CPC tends to resolve with favorable outcome in most cases.

Further case-control research is warranted.