Theoretical study for the inhibition ability of some bioactive imidazole derivatives against the Middle-East respiratory syndrome corona virus (MERS-Co)
Author
Source
ZANCO Journal of Pure and Applied Sciences
Issue
Vol. 31, Issue 2 (30 Apr. 2019), pp.71-78, 8 p.
Publisher
Salahaddin University-Erbil Department of Scientific Publications
Publication Date
2019-04-30
Country of Publication
Iraq
No. of Pages
8
Main Subjects
Topics
Abstract EN
The Severe Acute Respiratory Syndrome (SARS) is a serious viral life-threatening and mortal respiratory illness caused by SARS-CoV.
SARS-CoV plays an essential role in the viral replication cycle.
It is considered a potential target for SARS inhibitor development.
A series of twenty eight bioactive imidazole compounds as possible SARS-CoV inhibitors were designed and evaluated using computational calculations.
Possible binding interaction modes were proposed by molecular docking studies.
Among all studied compounds, compounds 5, 15 and 22 showed most potent inhibitory activity against SARS-CoV.
These results indicated that these inhibitors could be potentially developed into anti-SARS drugs.
American Psychological Association (APA)
Abd Allah, Hasan H.. 2019. Theoretical study for the inhibition ability of some bioactive imidazole derivatives against the Middle-East respiratory syndrome corona virus (MERS-Co). ZANCO Journal of Pure and Applied Sciences،Vol. 31, no. 2, pp.71-78.
https://search.emarefa.net/detail/BIM-897270
Modern Language Association (MLA)
Abd Allah, Hasan H.. Theoretical study for the inhibition ability of some bioactive imidazole derivatives against the Middle-East respiratory syndrome corona virus (MERS-Co). ZANCO Journal of Pure and Applied Sciences Vol. 31, no. 2 (2019), pp.71-78.
https://search.emarefa.net/detail/BIM-897270
American Medical Association (AMA)
Abd Allah, Hasan H.. Theoretical study for the inhibition ability of some bioactive imidazole derivatives against the Middle-East respiratory syndrome corona virus (MERS-Co). ZANCO Journal of Pure and Applied Sciences. 2019. Vol. 31, no. 2, pp.71-78.
https://search.emarefa.net/detail/BIM-897270
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 77-78
Record ID
BIM-897270