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Ameliorating effect of oral Guggulsterone administration in Imiquimod-induced psoriasis in mice
Other Title(s)
تأثير الاستخدام الفموي للغوغولستيرون لتخفيف الصدفية الناتجة عن الاستخدام الموضعي للايميكويمود في الفئران
Joint Authors
Zalzalah, Munaf Hashim
Khalil, Raghad Abd al-Salam
Source
Iraqi Journal of Pharmaceutical Sciences
Issue
Vol. 27, Issue 2 (31 Dec. 2018), pp.15-23, 9 p.
Publisher
University of Baghdad College of Pharmacy
Publication Date
2018-12-31
Country of Publication
Iraq
No. of Pages
9
Main Subjects
Topics
Abstract EN
Psoriasis is a common chronic skin condition characterized by infiltration of inflammatory cells into the epidermis and altered keratinocyte differentiation.
In this work, psoriasis was induced by an imiquimod 5 % cream, an immune response modifier that can induce psoriasis-like skin inflammation when applied topically in mice.
Guggulsterone prepared as a suspension and has been orally given to mice before imiquimod application.
The results of the current study showed that guggulsterone suspension can significantly reduce psoriasis area and severity index in (guggul suspension + imiquimod group as compared with both control group and (vehicle suspension + imiquimod ) group.
American Psychological Association (APA)
Khalil, Raghad Abd al-Salam& Zalzalah, Munaf Hashim. 2018. Ameliorating effect of oral Guggulsterone administration in Imiquimod-induced psoriasis in mice. Iraqi Journal of Pharmaceutical Sciences،Vol. 27, no. 2, pp.15-23.
https://search.emarefa.net/detail/BIM-897598
Modern Language Association (MLA)
Khalil, Raghad Abd al-Salam& Zalzalah, Munaf Hashim. Ameliorating effect of oral Guggulsterone administration in Imiquimod-induced psoriasis in mice. Iraqi Journal of Pharmaceutical Sciences Vol. 27, no. 2 (2018), pp.15-23.
https://search.emarefa.net/detail/BIM-897598
American Medical Association (AMA)
Khalil, Raghad Abd al-Salam& Zalzalah, Munaf Hashim. Ameliorating effect of oral Guggulsterone administration in Imiquimod-induced psoriasis in mice. Iraqi Journal of Pharmaceutical Sciences. 2018. Vol. 27, no. 2, pp.15-23.
https://search.emarefa.net/detail/BIM-897598
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 22-23
Record ID
BIM-897598