The effect of alcoholic extract of Borage officinalis on monoamine oxidase (MAO)‎ and acetylcholinesterase (AChE)‎ in human serum in vitro

Other Title(s)

تأثير المستخلص الكحولي لنبات Borage officinalis (لسان الثور)‎ على الفعالية الإنزيمية للأنزيمات Monoamin oxidase و Acetylcholinesterase في مصل الدم البشري

Author

Husayn, Zaynab Ghalib

Source

Iraq Journal of Market Research and Consumer Protection

Issue

Vol. 10, Issue 2 (31 Dec. 2018), pp.147-153, 7 p.

Publisher

University of Bagdad Market Research and Consumer Protection Center

Publication Date

2018-12-31

Country of Publication

Iraq

No. of Pages

7

Main Subjects

Botany

Topics

Abstract EN

This study was designed to show the inhibitory effect of different concentrations of alcoholic extract of Borage officinalis on the Monoamine oxidase (MAO) and Acetylcholinesterase (AChE) enzymes in human serum.

The results obtained from the study exhibited that alcoholic extract of Borage officinalis caused inhibition to enzymes activity with all concentrations of the extract.

The results also showed that when the concentration of the extract was (0.001 mg/ml), the percentage of inhibition was (4.3% with MAO and 15.2% with AChE) and this percentage increases until reaching up to (74.7% with MAO and 84.18% with AChE) when the concentration of the extract was (0.1 mg/ml).

From the kinetic parameters, studies found that alcoholic extract of Borage officinalis is acting as competitive inhibitor with MAO enzyme and as uncompetitive inhibitor with AChE enzyme.

American Psychological Association (APA)

Husayn, Zaynab Ghalib. 2018. The effect of alcoholic extract of Borage officinalis on monoamine oxidase (MAO) and acetylcholinesterase (AChE) in human serum in vitro. Iraq Journal of Market Research and Consumer Protection،Vol. 10, no. 2, pp.147-153.
https://search.emarefa.net/detail/BIM-897708

Modern Language Association (MLA)

Husayn, Zaynab Ghalib. The effect of alcoholic extract of Borage officinalis on monoamine oxidase (MAO) and acetylcholinesterase (AChE) in human serum in vitro. Iraq Journal of Market Research and Consumer Protection Vol. 10, no. 2 (2018), pp.147-153.
https://search.emarefa.net/detail/BIM-897708

American Medical Association (AMA)

Husayn, Zaynab Ghalib. The effect of alcoholic extract of Borage officinalis on monoamine oxidase (MAO) and acetylcholinesterase (AChE) in human serum in vitro. Iraq Journal of Market Research and Consumer Protection. 2018. Vol. 10, no. 2, pp.147-153.
https://search.emarefa.net/detail/BIM-897708

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references : p. 152-153

Record ID

BIM-897708