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Impact of blood transfusion on troponin i levels and outcomes after cardiac surgery : a cohort study
Joint Authors
al-Riyami, Arwa Z.
al-Lawati, Hatim
al-Sabti, Hilal Ali
Baskaran, Balan
Mukaddirov, Mirdavron
al-Khaburi, Murtada
Source
Issue
Vol. 34, Issue 1 (31 Jan. 2019), pp.14-19, 6 p.
Publisher
Publication Date
2019-01-31
Country of Publication
Oman
No. of Pages
6
Main Subjects
Topics
Abstract EN
Objectives : increased cardiac troponin i (ti) has been suggested to be a sensitive indicator of intraoperative myocardial injury.
we investigated the association of transfusion on ti levels post-surgery and outcomes in patients undergoing elective cardiac surgeries.
Methods : we conducted a retrospective review of 542 patients.
patients were divided into two groups based on ti levels at 24 hours (ti24) (> 6.5 μg/l vs.
≤ 6.5 μg/l).
the impact of transfusion on ti levels was estimated using logistic regression and adjusted for using a multivariable model that included aortic cross-clamp time and preoperative ejection fraction.
the effect of ti on the clinical outcomes was examined.
Results : red blood cell (rbc) transfusion was found to be associated with high ti levels (odds ratio (or) = 2.33, p = 0.007, 95% confidence interval (ci): 1.30–4.30).
a trend was observed when aortic cross-clamp time and preoperative ejection fraction were adjusted for (or = 2.06, p = 0.080, 95% ci: 0.90–4.70).
an association was found between aortic cross-clamp time and high ti levels in the multivariable model (or = 1.01, p = 0.028, 95% ci: 1.00–1.02).
elevated ti levels was associated with higher mortality (or = 4.15, p = 0.017, 95% ci: 1.29–13.08), renal failure (or = 2.99, p = 0.004, 95% ci: 1.41–6.32), and increased length of stay in-hospital (or = 4.50, p = 0.020, 95% ci: 0.69–8.30).
conclusions : rbc transfusion is associated with increased ti24 post-cardiac surgery and worse outcomes, albeit a confounding effect cannot be excluded.
larger studies are required to confirm these findings.
American Psychological Association (APA)
al-Riyami, Arwa Z.& al-Khaburi, Murtada& Baskaran, Balan& al-Lawati, Hatim& Mukaddirov, Mirdavron& al-Sabti, Hilal Ali. 2019. Impact of blood transfusion on troponin i levels and outcomes after cardiac surgery : a cohort study. Oman Medical Journal،Vol. 34, no. 1, pp.14-19.
https://search.emarefa.net/detail/BIM-898147
Modern Language Association (MLA)
al-Riyami, Arwa Z.…[et al.]. Impact of blood transfusion on troponin i levels and outcomes after cardiac surgery : a cohort study. Oman Medical Journal Vol. 34, no. 1 (Jan. 2019), pp.14-19.
https://search.emarefa.net/detail/BIM-898147
American Medical Association (AMA)
al-Riyami, Arwa Z.& al-Khaburi, Murtada& Baskaran, Balan& al-Lawati, Hatim& Mukaddirov, Mirdavron& al-Sabti, Hilal Ali. Impact of blood transfusion on troponin i levels and outcomes after cardiac surgery : a cohort study. Oman Medical Journal. 2019. Vol. 34, no. 1, pp.14-19.
https://search.emarefa.net/detail/BIM-898147
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 18-19
Record ID
BIM-898147